The role of electrodeposition conditions in creating MnO2-based flexible non-enzymatic glucose sensors
Rapid growth in diabetes morbidity compels researchers to develop an enzymeless alternative to currently used enzymatic glucose monitors. In relation to the target glucose electrooxidation reaction, a series of non-enzymatic flexible MnO2-based electrodes was fabricated by means of electrodeposition...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-07-01
|
| Series: | Next Materials |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949822825004332 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849319753876766720 |
|---|---|
| author | Ivan S. Filimonenkov Anna I. Mokhova Didar Zh. Kurzhumbaev Sergey A. Urvanov |
| author_facet | Ivan S. Filimonenkov Anna I. Mokhova Didar Zh. Kurzhumbaev Sergey A. Urvanov |
| author_sort | Ivan S. Filimonenkov |
| collection | DOAJ |
| description | Rapid growth in diabetes morbidity compels researchers to develop an enzymeless alternative to currently used enzymatic glucose monitors. In relation to the target glucose electrooxidation reaction, a series of non-enzymatic flexible MnO2-based electrodes was fabricated by means of electrodeposition. The effect of electrodeposition parameters (solution temperature, concentration, deposition potential) on morphological and electrochemical characteristics of prepared MnO2 samples was investigated. To exhibit practical prospects of electrodeposited MnO2 electrocatalysts for the in vivo use, glucose electrooxidation was performed in an isotonic NaCl-based phosphate-buffered saline with pH 7.40 containing physiological (1–30 mM) glucose concentrations. A rotating ring-disk electrode was applied to reveal differences in the electrodeposition process under various conditions as well as to solidly establish potentials of MnO2 cathodic dissolution and O2/Cl2 evolution at pH 7.40. For the most active sensor electrode with pronounced MnO2 surface architecture a linear square root concentration plot in the full physiological glucose range (1–30 mM) was demonstrated. Sensitivity values up to ca. 41.8 and 81.2 μA mM−0.5 cm−2 at 25 and 37 °C, respectively, were observed. Excellent reproducibility of the glucose oxidation current and good glucose selectivity of electrodeposited MnO2 in relation to some common interferent substances (fructose, galactose, xylose, ribose, urea, lactic acid, acetone, ascorbic acid, paracetamol) were revealed. |
| format | Article |
| id | doaj-art-08d181df75324336a960e3d2b57935b2 |
| institution | Kabale University |
| issn | 2949-8228 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Next Materials |
| spelling | doaj-art-08d181df75324336a960e3d2b57935b22025-08-20T03:50:21ZengElsevierNext Materials2949-82282025-07-01810091510.1016/j.nxmate.2025.100915The role of electrodeposition conditions in creating MnO2-based flexible non-enzymatic glucose sensorsIvan S. Filimonenkov0Anna I. Mokhova1Didar Zh. Kurzhumbaev2Sergey A. Urvanov3Technological Institute for Superhard and Novel Carbon Materials of National Research Centre “Kurchatov Institute”, 7A Tsentralnaya Street, Troitsk, Moscow 108840, Russia; Corresponding author.Technological Institute for Superhard and Novel Carbon Materials of National Research Centre “Kurchatov Institute”, 7A Tsentralnaya Street, Troitsk, Moscow 108840, RussiaTechnological Institute for Superhard and Novel Carbon Materials of National Research Centre “Kurchatov Institute”, 7A Tsentralnaya Street, Troitsk, Moscow 108840, Russia; Moscow Institute of Physics and Technology, 9 Institutsky lane, Dolgoprudny, Moscow Region 141700, RussiaTechnological Institute for Superhard and Novel Carbon Materials of National Research Centre “Kurchatov Institute”, 7A Tsentralnaya Street, Troitsk, Moscow 108840, RussiaRapid growth in diabetes morbidity compels researchers to develop an enzymeless alternative to currently used enzymatic glucose monitors. In relation to the target glucose electrooxidation reaction, a series of non-enzymatic flexible MnO2-based electrodes was fabricated by means of electrodeposition. The effect of electrodeposition parameters (solution temperature, concentration, deposition potential) on morphological and electrochemical characteristics of prepared MnO2 samples was investigated. To exhibit practical prospects of electrodeposited MnO2 electrocatalysts for the in vivo use, glucose electrooxidation was performed in an isotonic NaCl-based phosphate-buffered saline with pH 7.40 containing physiological (1–30 mM) glucose concentrations. A rotating ring-disk electrode was applied to reveal differences in the electrodeposition process under various conditions as well as to solidly establish potentials of MnO2 cathodic dissolution and O2/Cl2 evolution at pH 7.40. For the most active sensor electrode with pronounced MnO2 surface architecture a linear square root concentration plot in the full physiological glucose range (1–30 mM) was demonstrated. Sensitivity values up to ca. 41.8 and 81.2 μA mM−0.5 cm−2 at 25 and 37 °C, respectively, were observed. Excellent reproducibility of the glucose oxidation current and good glucose selectivity of electrodeposited MnO2 in relation to some common interferent substances (fructose, galactose, xylose, ribose, urea, lactic acid, acetone, ascorbic acid, paracetamol) were revealed.http://www.sciencedirect.com/science/article/pii/S2949822825004332Non-enzymatic glucose oxidationManganese dioxideElectrodepositionContinuous glucose monitoringDiabetes |
| spellingShingle | Ivan S. Filimonenkov Anna I. Mokhova Didar Zh. Kurzhumbaev Sergey A. Urvanov The role of electrodeposition conditions in creating MnO2-based flexible non-enzymatic glucose sensors Next Materials Non-enzymatic glucose oxidation Manganese dioxide Electrodeposition Continuous glucose monitoring Diabetes |
| title | The role of electrodeposition conditions in creating MnO2-based flexible non-enzymatic glucose sensors |
| title_full | The role of electrodeposition conditions in creating MnO2-based flexible non-enzymatic glucose sensors |
| title_fullStr | The role of electrodeposition conditions in creating MnO2-based flexible non-enzymatic glucose sensors |
| title_full_unstemmed | The role of electrodeposition conditions in creating MnO2-based flexible non-enzymatic glucose sensors |
| title_short | The role of electrodeposition conditions in creating MnO2-based flexible non-enzymatic glucose sensors |
| title_sort | role of electrodeposition conditions in creating mno2 based flexible non enzymatic glucose sensors |
| topic | Non-enzymatic glucose oxidation Manganese dioxide Electrodeposition Continuous glucose monitoring Diabetes |
| url | http://www.sciencedirect.com/science/article/pii/S2949822825004332 |
| work_keys_str_mv | AT ivansfilimonenkov theroleofelectrodepositionconditionsincreatingmno2basedflexiblenonenzymaticglucosesensors AT annaimokhova theroleofelectrodepositionconditionsincreatingmno2basedflexiblenonenzymaticglucosesensors AT didarzhkurzhumbaev theroleofelectrodepositionconditionsincreatingmno2basedflexiblenonenzymaticglucosesensors AT sergeyaurvanov theroleofelectrodepositionconditionsincreatingmno2basedflexiblenonenzymaticglucosesensors AT ivansfilimonenkov roleofelectrodepositionconditionsincreatingmno2basedflexiblenonenzymaticglucosesensors AT annaimokhova roleofelectrodepositionconditionsincreatingmno2basedflexiblenonenzymaticglucosesensors AT didarzhkurzhumbaev roleofelectrodepositionconditionsincreatingmno2basedflexiblenonenzymaticglucosesensors AT sergeyaurvanov roleofelectrodepositionconditionsincreatingmno2basedflexiblenonenzymaticglucosesensors |