The role of electrodeposition conditions in creating MnO2-based flexible non-enzymatic glucose sensors
Rapid growth in diabetes morbidity compels researchers to develop an enzymeless alternative to currently used enzymatic glucose monitors. In relation to the target glucose electrooxidation reaction, a series of non-enzymatic flexible MnO2-based electrodes was fabricated by means of electrodeposition...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-07-01
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| Series: | Next Materials |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949822825004332 |
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| Summary: | Rapid growth in diabetes morbidity compels researchers to develop an enzymeless alternative to currently used enzymatic glucose monitors. In relation to the target glucose electrooxidation reaction, a series of non-enzymatic flexible MnO2-based electrodes was fabricated by means of electrodeposition. The effect of electrodeposition parameters (solution temperature, concentration, deposition potential) on morphological and electrochemical characteristics of prepared MnO2 samples was investigated. To exhibit practical prospects of electrodeposited MnO2 electrocatalysts for the in vivo use, glucose electrooxidation was performed in an isotonic NaCl-based phosphate-buffered saline with pH 7.40 containing physiological (1–30 mM) glucose concentrations. A rotating ring-disk electrode was applied to reveal differences in the electrodeposition process under various conditions as well as to solidly establish potentials of MnO2 cathodic dissolution and O2/Cl2 evolution at pH 7.40. For the most active sensor electrode with pronounced MnO2 surface architecture a linear square root concentration plot in the full physiological glucose range (1–30 mM) was demonstrated. Sensitivity values up to ca. 41.8 and 81.2 μA mM−0.5 cm−2 at 25 and 37 °C, respectively, were observed. Excellent reproducibility of the glucose oxidation current and good glucose selectivity of electrodeposited MnO2 in relation to some common interferent substances (fructose, galactose, xylose, ribose, urea, lactic acid, acetone, ascorbic acid, paracetamol) were revealed. |
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| ISSN: | 2949-8228 |