The sexual dysfunction in women with thyroid disorders: a meta-analysis

Abstract Background Thyroid disorders are common endocrine conditions impacting multiple organs, including the reproductive system and often lead to sexual dysfunction. These effects can vary by gender; for example, women with hypothyroidism frequently experience reduced libido. Low thyroid hormone...

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Main Authors: Nader Salari, Pegah Heidarian, Framarz Jalili, Fateme Babajani, Shamarina Shohaimi, Maryam Nasirian, Masoud Mohammadi
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Endocrine Disorders
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Online Access:https://doi.org/10.1186/s12902-024-01817-9
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author Nader Salari
Pegah Heidarian
Framarz Jalili
Fateme Babajani
Shamarina Shohaimi
Maryam Nasirian
Masoud Mohammadi
author_facet Nader Salari
Pegah Heidarian
Framarz Jalili
Fateme Babajani
Shamarina Shohaimi
Maryam Nasirian
Masoud Mohammadi
author_sort Nader Salari
collection DOAJ
description Abstract Background Thyroid disorders are common endocrine conditions impacting multiple organs, including the reproductive system and often lead to sexual dysfunction. These effects can vary by gender; for example, women with hypothyroidism frequently experience reduced libido. Low thyroid hormone levels are also linked to vaginal dryness, causing discomfort, especially during intercourse. This study aims to assess the global prevalence of sexual dysfunction in women with thyroid disorders. Methods Systematic searches were performed across electronic databases, including PubMed, Scopus, Web of Science, Embase, ScienceDirect and Google Scholar, to retrieve studies reporting the prevalence of sexual dysfunction in patients with thyroid disorders up to February 8, 2024. Inclusion criteria comprised studies that reported on the prevalence of female sexual dysfunction (FSD) in patients with thyroid disorders and studies published in English available full text. Exclusion criteria included case studies, intervention studies, studies with incomplete information, repeated studies and those not written in English. Cross-sectional studies were the primary study design included. Data were analyzed using the Comprehensive Meta-Analysis software (Version 2). Results Analysis of nine studies, involving a total sample size of 1013, found an overall prevalence of sexual dysfunction in women with thyroid disorders to be 44.8% (95% CI: 33.8–56.2). Given the substantial reporting of sexual dysfunction among women with either hypothyroidism or hyperthyroidism, subgroup analyses were conducted. The prevalence of sexual dysfunction was 41.8% (95% CI: 26.3–59) among women with hypothyroidism and 59.6% (95% CI: 50.5–68.1) among those with hyperthyroidism. Conclusion The notable prevalence of sexual dysfunction in women with thyroid disorders highlights the for increased awareness among this population. Targeted awareness initiatives may help mitigate the occurrence of sexual dysfunction and its adverse effects, improving overall quality of life for affected women. Clinical trial number Not applicable.
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spelling doaj-art-08cd4daaec1e41bf8b866cd377ad34312025-08-20T02:39:37ZengBMCBMC Endocrine Disorders1472-68232024-12-012411710.1186/s12902-024-01817-9The sexual dysfunction in women with thyroid disorders: a meta-analysisNader Salari0Pegah Heidarian1Framarz Jalili2Fateme Babajani3Shamarina Shohaimi4Maryam Nasirian5Masoud Mohammadi6Department of Biostatistics, School of Health, Kermanshah University of Medical SciencesStudent Research Committee, Kermanshah University of Medical SciencesSchool of Health Administration, Dalhousie UniversityDepartment of Clinical Psychology, Faculty of Medicine, Kermanshah University of Medical SciencesDepartment of Biology, Faculty of Science, University Putra MalaysiaDepartment of Epidemiology and Biostatistics, Faculty of Health, Isfahan University of Medical Science3. Research Center for Social Determinants of Health, Jahrom University of Medical SciencesAbstract Background Thyroid disorders are common endocrine conditions impacting multiple organs, including the reproductive system and often lead to sexual dysfunction. These effects can vary by gender; for example, women with hypothyroidism frequently experience reduced libido. Low thyroid hormone levels are also linked to vaginal dryness, causing discomfort, especially during intercourse. This study aims to assess the global prevalence of sexual dysfunction in women with thyroid disorders. Methods Systematic searches were performed across electronic databases, including PubMed, Scopus, Web of Science, Embase, ScienceDirect and Google Scholar, to retrieve studies reporting the prevalence of sexual dysfunction in patients with thyroid disorders up to February 8, 2024. Inclusion criteria comprised studies that reported on the prevalence of female sexual dysfunction (FSD) in patients with thyroid disorders and studies published in English available full text. Exclusion criteria included case studies, intervention studies, studies with incomplete information, repeated studies and those not written in English. Cross-sectional studies were the primary study design included. Data were analyzed using the Comprehensive Meta-Analysis software (Version 2). Results Analysis of nine studies, involving a total sample size of 1013, found an overall prevalence of sexual dysfunction in women with thyroid disorders to be 44.8% (95% CI: 33.8–56.2). Given the substantial reporting of sexual dysfunction among women with either hypothyroidism or hyperthyroidism, subgroup analyses were conducted. The prevalence of sexual dysfunction was 41.8% (95% CI: 26.3–59) among women with hypothyroidism and 59.6% (95% CI: 50.5–68.1) among those with hyperthyroidism. Conclusion The notable prevalence of sexual dysfunction in women with thyroid disorders highlights the for increased awareness among this population. Targeted awareness initiatives may help mitigate the occurrence of sexual dysfunction and its adverse effects, improving overall quality of life for affected women. Clinical trial number Not applicable.https://doi.org/10.1186/s12902-024-01817-9Female sexual dysfunctionFSDThyroidMeta-analysis
spellingShingle Nader Salari
Pegah Heidarian
Framarz Jalili
Fateme Babajani
Shamarina Shohaimi
Maryam Nasirian
Masoud Mohammadi
The sexual dysfunction in women with thyroid disorders: a meta-analysis
BMC Endocrine Disorders
Female sexual dysfunction
FSD
Thyroid
Meta-analysis
title The sexual dysfunction in women with thyroid disorders: a meta-analysis
title_full The sexual dysfunction in women with thyroid disorders: a meta-analysis
title_fullStr The sexual dysfunction in women with thyroid disorders: a meta-analysis
title_full_unstemmed The sexual dysfunction in women with thyroid disorders: a meta-analysis
title_short The sexual dysfunction in women with thyroid disorders: a meta-analysis
title_sort sexual dysfunction in women with thyroid disorders a meta analysis
topic Female sexual dysfunction
FSD
Thyroid
Meta-analysis
url https://doi.org/10.1186/s12902-024-01817-9
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