Novel Integration of Spatial and Single-Cell Omics Data Sets Enables Deeper Insights into IPF Pathogenesis

Novel Integration of Spatial and Single-Cell Omics Data Sets Enables Deeper Insights into IPF Pathogenesis

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterized by repetitive alveolar injuries with excessive deposition of extracellular matrix (ECM) proteins. A crucial need in understanding IPF pathogenesis is identifying cell types associated with histopathological regions, part...

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Bibliographic Details
Main Authors: Fei Wang, Liang Jin, Xue Wang, Baoliang Cui, Yingli Yang, Lori Duggan, Annette Schwartz Sterman, Sarah M. Lloyd, Lisa A. Hazelwood, Neha Chaudhary, Bhupinder Bawa, Lucy A. Phillips, Yupeng He, Yu Tian
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Proteomes
Subjects:
Idiopathic pulmonary fibrosis
spatial transcriptomics
laser capture microdissection
spatial proteomics
mass spectrometry
scRNA-seq
Online Access:https://www.mdpi.com/2227-7382/13/1/3
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