Mechanistic insights into the therapeutic effects on liver fibrosis in Wilson's disease: a transcriptomic and network pharmacology-based approach

Mechanistic insights into the therapeutic effects on liver fibrosis in Wilson's disease: a transcriptomic and network pharmacology-based approach

BackgroundThe mechanism of the Bushen Huoxue Huazhuo Formula (BSHXHZF) in treating Wilson's disease (WD) liver fibrosis was investigated in this study using transcriptomics, network pharmacology, and molecular docking approaches.MethodsDifferentially expressed long non-coding RNAs (DELncRNAs) a...

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Bibliographic Details
Main Authors: Ying Ma, Yue Pu, Hong Chen, Lei Zhou, Bo Yang, Xiaofeng Huang, Juan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Medicine
Subjects:
Bushen Huoxue Huazhuo Formula
Wilson's disease
liver fibrosis
LncRNA
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1581623/full
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