Nonobstructive azoospermia: an etiologic review

Nonobstructive azoospermia: an etiologic review

Azoospermia is the complete absence of spermatozoa in the ejaculate in two or more semen analyses after centrifugation. Nonobstructive azoospermia (NOA) represents the most severe form of male factor infertility accounting for 10%–15% of cases and stems from an impairment to spermatogenesis. Underst...

Full description

Saved in:

Bibliographic Details
Main Authors:	Logan Hubbard, Amarnath Rambhatla, Sidney Glina
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2025-05-01
Series:	Asian Journal of Andrology
Subjects:	hypergonadotropic hypogonadism hypogonadotropic hypogonadism male factor infertility nonobstructive azoospermia
Online Access:	https://journals.lww.com/10.4103/aja202472
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Differentiation between nonobstructive azoospermia and obstructive azoospermia: then and now
by: Logan Hubbard, et al.
Published: (2025-05-01)

A review of testicular histopathology in nonobstructive azoospermia
by: Taymour Mostafa, et al.
Published: (2025-05-01)

Case report of successful live birth in an infertile couple with male idiopathic hypogonadotropic hypogonadism/azoospermia and atypical polypoid adenomyoma of the uterus
by: K. Okuno, et al.
Published: (2020-12-01)

Surgical treatment of nonobstructive azoospermy, caused by hypergonadotropic hypogonadism
by: О. D. Nikitin
Published: (2018-04-01)

Anatomical considerations, testicular, and scrotal anatomy of nonobstructive azoospermia patients
by: Hao-Cheng Lin, et al.
Published: (2025-05-01)

KIF2C Deletion Causes Meiotic Abnormalities and Nonobstructive Azoospermia in Mice
by: Hiroaki Kitakaze, et al.
Published: (2025-01-01)

Diagnostic algorithm in men suspected with nonobstructive azoospermia
by: Mahdi Bazzi, et al.
Published: (2025-05-01)

Hypogonadotropic hypogonadism as a cause of NOA and its treatment
by: Gianmaria Salvio, et al.
Published: (2025-05-01)

Non obstructive azoospermia as the only indicator of focal segmental glomerulosclerosis and chronic kidney failure: A case report
by: Raneen Sawaid Kaiyal, et al.
Published: (2025-05-01)

Epigenetics of nonobstructive azoospermia
by: Sezgin Gunes, et al.
Published: (2025-05-01)

Comparison of FSH Pre-treatment Versus Upfront hCG and FSH Regimens for Inducing Spermatogenesis in Congenital Hypogonadotropic Hypogonadism: A Pilot Study
by: Japleen Kaur, et al.
Published: (2025-05-01)

Varicocele and nonobstructive azoospermia
by: Parviz K Kavoussi, et al.
Published: (2025-05-01)

Gordon Holmes syndrome - A rare case of ataxia, hypogonadism, and cerebral white matter changes with expanding phenotype and review of cerebellar ataxia with hypogonadism
by: Vishal Chandra Sharma, et al.
Published: (2025-01-01)

Galactosemia and timing of puberty: a case report of early diagnosed hypergonadotropic hypogonadism
by: Cecilia Lugarà, et al.
Published: (2025-02-01)

Isolated Hypogonadotropic Hypogonadism in a Young Woman with Primary Amenorrhoea
by: Zalkha Al Kharusi, et al.
Published: (2024-11-01)

Association of higher serum follicle-stimulating hormone levels with successful microdissection testicular sperm extraction outcomes in nonobstructive azoospermic men with reduced testicular volumes
by: Ming-Zhe Song, et al.
Published: (2025-05-01)

Epigenetics of Hypogonadotropic Hypogonadism: Molecular Mimicry between Severe Acute Respiratory Syndrome Coronavirus 2 and KISSR
by: Darja Kanduc
Published: (2023-06-01)

Novel biallelic MCMDC2 variants were associated with meiotic arrest and nonobstructive azoospermia
by: Hao-Wei Bai, et al.
Published: (2025-03-01)

Micromapping testicular sperm extraction: A new technique for microscopic testicular sperm extraction in nonobstructive azoospermia
by: Toshihiro Tai, et al.
Published: (2024-01-01)

A Rare Cause of Hypergonadotropic Hypogonadism: Transaldolase Deficiency in Two Siblings
by: Melek Yıldız, et al.
Published: (2025-03-01)

AN ORPHAN PHENOTYPE OF CARDIOGENITAL LAMINOPATHY — MALOUF SYNDROME
by: T. G. Vaykhanskaya, et al.
Published: (2016-11-01)

Case Report: Hypergonadotropic hypogonadism in an elite athlete with variant in FSH receptor gene—clinical and sports implications of proper diagnosis
by: Monika Skrzypiec-Spring, et al.
Published: (2025-08-01)

Clinical, diagnostic, and therapeutic aspects of Kallmann syndrome with an FGFR1 gene variant in a female adolescent
by: Karina Matusiak, et al.
Published: (2025-03-01)

TUMORAL AND NON TUMORAL PITUITARY LESIONS AND REPRODUCTIVE SYSTEM
by: I. A. Ilovayskaya
Published: (2012-05-01)

PREDICTION BACKUP TESTICULAR FUNCTION IN PATIENTS WITH NONOBSTRUCTIVE AZOOSPERMIA
by: N. G. Kul’chenko, et al.
Published: (2016-09-01)

Changes in Testosterone Levels Following Surgical Sperm Retrieval in Men with Non-Obstructive Azoospermia: Systematic Review and Meta-Analysis
by: Wael Zohdy, et al.
Published: (2025-07-01)

Varicocelectomy in Patients with Non-obstructive Azoospermia
by: Cevahir Özer, et al.
Published: (2019-12-01)

Predictors of sperm retrieval success in first-time and repeated Micro-TESE for nonobstructive azoospermia
by: Sulieman Alriyalat, et al.
Published: (2025-12-01)

Fresh Gametes Might Get Better Clinical Results than Cryopreserved Sperm or Oocytes for Nonobstructive Azoospermia Patients Underwent micro-TESE
by: Yapeng Wang, et al.
Published: (2022-06-01)

Phosphomannomutase 2-congenital disorder of glycosylation: exploring the role of N-glycosylation on the endocrine axes
by: Giulia Del Medico, et al.
Published: (2025-07-01)

Evaluation of DAZ1 Gene Expression in Spermatogenic Failure among Infertile Non-Obstructive Azoospermic Iraqi Males
by: I Abd Ali Al-Humairi, et al.
Published: (2024-03-01)

Gonadotropins in hypogonadotropic hypogonadism in adolescents: prospects of treatment
by: Yu. L. Skorodok, et al.
Published: (2021-06-01)

Microdissection testicular sperm extraction for men with nonobstructive azoospermia who have a testicular tumor in situ at the time of sperm retrieval
by: Hao-Cheng Lin, et al.
Published: (2025-05-01)

Understanding the Role of Alcohol in Metabolic Dysfunction and Male Infertility
by: Valentina Annamaria Genchi, et al.
Published: (2024-11-01)

De novo retrotransposon insertion into the FGFR1 gene in a boy with congenital hypogonadotropic hypogonadism: a case report
by: Kentaro Sawano, et al.
Published: (2025-06-01)

Turner syndrome and postpubertal Empty sella syndrome: a case report and literature review
by: Fanyu Lin, et al.
Published: (2025-06-01)

Comparison of outcomes between pulsatile gonadotropin releasing hormone and combined gonadotropin therapy of spermatogenesis in patients with congenital hypogonadotropic hypogonadism
by: Yi Zheng, et al.
Published: (2025-03-01)

Differentiating between obstructive and non‐obstructive azoospermia: A machine learning‐based approach
by: Abdolreza Haghpanah, et al.
Published: (2025-02-01)

Medical treatment prior to micro-TESE
by: Sujoy Dasgupta, et al.
Published: (2025-05-01)

KLB, encoding β‐Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism
by: Cheng Xu, et al.
Published: (2017-07-01)