Clinical case of combined intestinal infection caused by enteroaggregative Escherichia coli and toxigenic strain Clostridium difficile in a child with cystic fibrosis
The goal is to study the peculiarities of the clinical picture and the distant outcome of intestinal infection due to enteroaggregative escherichiosis and the toxigenic strain of C. difficile in a child with cystic fibrosis.Material and methods. To verify the etiology of intestinal infection, the fo...
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2021-10-01
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| Series: | Журнал инфектологии |
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| Online Access: | https://journal.niidi.ru/jofin/article/view/1232 |
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| author | N. V. Gonchar O. I. Klimova I. V. Razd'yakonova A. V. Orlov A. S. Kvetnaya |
| author_facet | N. V. Gonchar O. I. Klimova I. V. Razd'yakonova A. V. Orlov A. S. Kvetnaya |
| author_sort | N. V. Gonchar |
| collection | DOAJ |
| description | The goal is to study the peculiarities of the clinical picture and the distant outcome of intestinal infection due to enteroaggregative escherichiosis and the toxigenic strain of C. difficile in a child with cystic fibrosis.Material and methods. To verify the etiology of intestinal infection, the following studies were conducted. — fecal PCR “OKI-screen” tests to detect viral and bacterial pathogens, fecal bacteriopsy for pathogenic and opportunistic microbes; determination of C. difficile A and B toxins in feces by enzyme-linked fluorescence analysis.Results. The combined intestinal infection caused by en-teroaggregative escherichiosis and a toxigenic strain of C. difficile, in a child with pulmonary-intestinal form of cystic fibrosis was characterized by a wavy course, a pronounced intoxication syndrome, excicosis, hemorrhagic enterocolitis, signs of systemic and local inflammation, metabolic disorders. There were no recurrences of C. difficile-infection in catamnese.Conclusion. It is necessary to continue research on the course of intestinal infections caused by bacterial associations of pathogens. |
| format | Article |
| id | doaj-art-08c0d693dcca4f479ff257ccc44425b4 |
| institution | Kabale University |
| issn | 2072-6732 |
| language | Russian |
| publishDate | 2021-10-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj-art-08c0d693dcca4f479ff257ccc44425b42025-08-20T03:38:30ZrusJournal InfectologyЖурнал инфектологии2072-67322021-10-0113314314910.22625/2072-6732-2021-13-3-143-149926Clinical case of combined intestinal infection caused by enteroaggregative Escherichia coli and toxigenic strain Clostridium difficile in a child with cystic fibrosisN. V. Gonchar0O. I. Klimova1I. V. Razd'yakonova2A. V. Orlov3A. S. Kvetnaya4Pediatric Research and Clinical Center for Infectious Diseases; North-Western State Medical University named after I.I. MechnikovPediatric Research and Clinical Center for Infectious DiseasesPediatric Research and Clinical Center for Infectious DiseasesNorth-Western State Medical University named after I.I. Mechnikov; St. Olga Children's city hospital № 4Pediatric Research and Clinical Center for Infectious DiseasesThe goal is to study the peculiarities of the clinical picture and the distant outcome of intestinal infection due to enteroaggregative escherichiosis and the toxigenic strain of C. difficile in a child with cystic fibrosis.Material and methods. To verify the etiology of intestinal infection, the following studies were conducted. — fecal PCR “OKI-screen” tests to detect viral and bacterial pathogens, fecal bacteriopsy for pathogenic and opportunistic microbes; determination of C. difficile A and B toxins in feces by enzyme-linked fluorescence analysis.Results. The combined intestinal infection caused by en-teroaggregative escherichiosis and a toxigenic strain of C. difficile, in a child with pulmonary-intestinal form of cystic fibrosis was characterized by a wavy course, a pronounced intoxication syndrome, excicosis, hemorrhagic enterocolitis, signs of systemic and local inflammation, metabolic disorders. There were no recurrences of C. difficile-infection in catamnese.Conclusion. It is necessary to continue research on the course of intestinal infections caused by bacterial associations of pathogens.https://journal.niidi.ru/jofin/article/view/1232combined intestinal infectionschildrenbacterial pathogensthe clinical picture |
| spellingShingle | N. V. Gonchar O. I. Klimova I. V. Razd'yakonova A. V. Orlov A. S. Kvetnaya Clinical case of combined intestinal infection caused by enteroaggregative Escherichia coli and toxigenic strain Clostridium difficile in a child with cystic fibrosis Журнал инфектологии combined intestinal infections children bacterial pathogens the clinical picture |
| title | Clinical case of combined intestinal infection caused by enteroaggregative Escherichia coli and toxigenic strain Clostridium difficile in a child with cystic fibrosis |
| title_full | Clinical case of combined intestinal infection caused by enteroaggregative Escherichia coli and toxigenic strain Clostridium difficile in a child with cystic fibrosis |
| title_fullStr | Clinical case of combined intestinal infection caused by enteroaggregative Escherichia coli and toxigenic strain Clostridium difficile in a child with cystic fibrosis |
| title_full_unstemmed | Clinical case of combined intestinal infection caused by enteroaggregative Escherichia coli and toxigenic strain Clostridium difficile in a child with cystic fibrosis |
| title_short | Clinical case of combined intestinal infection caused by enteroaggregative Escherichia coli and toxigenic strain Clostridium difficile in a child with cystic fibrosis |
| title_sort | clinical case of combined intestinal infection caused by enteroaggregative escherichia coli and toxigenic strain clostridium difficile in a child with cystic fibrosis |
| topic | combined intestinal infections children bacterial pathogens the clinical picture |
| url | https://journal.niidi.ru/jofin/article/view/1232 |
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