Cardiorenal Syndrome in Acute Heart Failure Syndromes
Impaired cardiac function leads to activation of the neurohumoral axis, sodium and water retention, congestion and ultimately impaired kidney function. This sequence of events has been termed the Cardiorenal Syndrome. This is different from the increase in cardiovascular complications which occur wi...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Nephrology |
| Online Access: | http://dx.doi.org/10.4061/2011/293938 |
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| _version_ | 1849305063478001664 |
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| author | Mohammad Sarraf Robert W. Schrier |
| author_facet | Mohammad Sarraf Robert W. Schrier |
| author_sort | Mohammad Sarraf |
| collection | DOAJ |
| description | Impaired cardiac function leads to activation of the neurohumoral axis, sodium and water retention, congestion and ultimately impaired kidney function. This sequence of events has been termed the Cardiorenal Syndrome. This is different from the increase in cardiovascular complications which occur with primary kidney disease, that is, the so-called Renocardiac Syndrome. The present review discusses the pathogenesis of the Cardiorenal Syndrome followed by the benefits and potential deleterious effects of pharmacological agents that have been used in this setting. The agents discussed are diuretics, aquaretics, natriuretic peptides, vasodilators, inotropes and adenosine α1 receptor antagonists. The potential role of ultrafiltration is also briefly discussed. |
| format | Article |
| id | doaj-art-08bfae748c6843d89aa6dafd406c853f |
| institution | Kabale University |
| issn | 2090-214X 2090-2158 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Nephrology |
| spelling | doaj-art-08bfae748c6843d89aa6dafd406c853f2025-08-20T03:55:33ZengWileyInternational Journal of Nephrology2090-214X2090-21582011-01-01201110.4061/2011/293938293938Cardiorenal Syndrome in Acute Heart Failure SyndromesMohammad Sarraf0Robert W. Schrier1University of Minnesota, USAUniversity of Colorado, USAImpaired cardiac function leads to activation of the neurohumoral axis, sodium and water retention, congestion and ultimately impaired kidney function. This sequence of events has been termed the Cardiorenal Syndrome. This is different from the increase in cardiovascular complications which occur with primary kidney disease, that is, the so-called Renocardiac Syndrome. The present review discusses the pathogenesis of the Cardiorenal Syndrome followed by the benefits and potential deleterious effects of pharmacological agents that have been used in this setting. The agents discussed are diuretics, aquaretics, natriuretic peptides, vasodilators, inotropes and adenosine α1 receptor antagonists. The potential role of ultrafiltration is also briefly discussed.http://dx.doi.org/10.4061/2011/293938 |
| spellingShingle | Mohammad Sarraf Robert W. Schrier Cardiorenal Syndrome in Acute Heart Failure Syndromes International Journal of Nephrology |
| title | Cardiorenal Syndrome in Acute Heart Failure Syndromes |
| title_full | Cardiorenal Syndrome in Acute Heart Failure Syndromes |
| title_fullStr | Cardiorenal Syndrome in Acute Heart Failure Syndromes |
| title_full_unstemmed | Cardiorenal Syndrome in Acute Heart Failure Syndromes |
| title_short | Cardiorenal Syndrome in Acute Heart Failure Syndromes |
| title_sort | cardiorenal syndrome in acute heart failure syndromes |
| url | http://dx.doi.org/10.4061/2011/293938 |
| work_keys_str_mv | AT mohammadsarraf cardiorenalsyndromeinacuteheartfailuresyndromes AT robertwschrier cardiorenalsyndromeinacuteheartfailuresyndromes |