Myasthenia gravis as one of paraneoplastic neurological syndromes associated with small cell lung cancer. Case report

Myasthenia gravis associated with extrathymic malignancies is a rarely diagnosed pathology in clinical practice. We report a case of myasthenia gravis-like syndrome associated with small cell lung cancer. A male patient has been diagnosed with 3 different paraneoplastic neurological syndromes: sens...

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Bibliographic Details
Main Authors: R. Bunevičiūtė, R. Masaitienė, A. Klimašauskienė
Format: Article
Language:English
Published: Vilnius University Press 2018-03-01
Series:Neurologijos seminarai
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Online Access:https://www.journals.vu.lt/neurologijos_seminarai/article/view/27854
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Summary:Myasthenia gravis associated with extrathymic malignancies is a rarely diagnosed pathology in clinical practice. We report a case of myasthenia gravis-like syndrome associated with small cell lung cancer. A male patient has been diagnosed with 3 different paraneoplastic neurological syndromes: sensorimotor polyneuropathy, limbic encephalitis and myasthenia gravis-like syndrome which was confirmed by positive repetitive nerve stimulation test. The causal association between small cell lung cancer and myasthenia gravis as a paraneoplastic neurological syndrome (PNS) has not been officially confirmed yet. However, there is increasing evidence in the literature, that myasthenia gravis could be one of the PNS phenotypes of non-thymomatous malignancies.
ISSN:1392-3064
2424-5917