Complexation and Antimicrobial Studies of Some Divalent Metal Chelates

Metal chelates of Ni(II) and Cu(II) with the ligand 5-acetamido-1,3,4-thiadiazole-2-sulphonamide have been synthesized. The isolated compounds have been characterized by elemental analysis, molar conductivity, magnetic moment, electronic and IR spectral studies. The analytical data reflects the meta...

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Main Authors: Suparna Ghosh, Suman Malik
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2010/252075
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author Suparna Ghosh
Suman Malik
author_facet Suparna Ghosh
Suman Malik
author_sort Suparna Ghosh
collection DOAJ
description Metal chelates of Ni(II) and Cu(II) with the ligand 5-acetamido-1,3,4-thiadiazole-2-sulphonamide have been synthesized. The isolated compounds have been characterized by elemental analysis, molar conductivity, magnetic moment, electronic and IR spectral studies. The analytical data reflects the metal to ligand stoichiometry to be 1: 2. The conductivity data of the complexes also suggests their non-electrolytic nature. The stability constants and free energy change for the complexes have been calculated.. Ligand and their complexes have been screened for their biological activity and the data show good activity of these complexes and ligands.
format Article
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institution Kabale University
issn 0973-4945
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language English
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spelling doaj-art-08a2b3f1c5da416c83aceedf02dc96732025-08-20T03:55:33ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-01741391139510.1155/2010/252075Complexation and Antimicrobial Studies of Some Divalent Metal ChelatesSuparna Ghosh0Suman Malik1Department of Chemistry, S.V. College, Bairagarh, Bhopal-462030, IndiaDepartment of Chemistry, S.V. College, Bairagarh, Bhopal-462030, IndiaMetal chelates of Ni(II) and Cu(II) with the ligand 5-acetamido-1,3,4-thiadiazole-2-sulphonamide have been synthesized. The isolated compounds have been characterized by elemental analysis, molar conductivity, magnetic moment, electronic and IR spectral studies. The analytical data reflects the metal to ligand stoichiometry to be 1: 2. The conductivity data of the complexes also suggests their non-electrolytic nature. The stability constants and free energy change for the complexes have been calculated.. Ligand and their complexes have been screened for their biological activity and the data show good activity of these complexes and ligands.http://dx.doi.org/10.1155/2010/252075
spellingShingle Suparna Ghosh
Suman Malik
Complexation and Antimicrobial Studies of Some Divalent Metal Chelates
E-Journal of Chemistry
title Complexation and Antimicrobial Studies of Some Divalent Metal Chelates
title_full Complexation and Antimicrobial Studies of Some Divalent Metal Chelates
title_fullStr Complexation and Antimicrobial Studies of Some Divalent Metal Chelates
title_full_unstemmed Complexation and Antimicrobial Studies of Some Divalent Metal Chelates
title_short Complexation and Antimicrobial Studies of Some Divalent Metal Chelates
title_sort complexation and antimicrobial studies of some divalent metal chelates
url http://dx.doi.org/10.1155/2010/252075
work_keys_str_mv AT suparnaghosh complexationandantimicrobialstudiesofsomedivalentmetalchelates
AT sumanmalik complexationandantimicrobialstudiesofsomedivalentmetalchelates