Antioxidant and Antibacterial Activity of Tanacetum spp. Essential Oil and Chemical Components

Introduction: The members of the genus Tanacetum are important medicinal plants. This study investigated the chemical composition and antibacterial activity of Tanacetum lingulatum and Tanacetum polycephalum essential oils on human infectious bacteria. Methods: The aerial part of two plants were...

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Main Author: Mostafa Alamholo1
Format: Article
Language:English
Published: Pasteur Institute of Iran 2022-03-01
Series:Journal of Medical Microbiology and Infectious Diseases
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Online Access:https://jommid.pasteur.ac.ir/article-1-356-en.html
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author Mostafa Alamholo1
author_facet Mostafa Alamholo1
author_sort Mostafa Alamholo1
collection DOAJ
description Introduction: The members of the genus Tanacetum are important medicinal plants. This study investigated the chemical composition and antibacterial activity of Tanacetum lingulatum and Tanacetum polycephalum essential oils on human infectious bacteria. Methods: The aerial part of two plants were collected from Urmia Province, Iran. The essential oils were extracted using a Clevenger device. The antibacterial effect of essential oils was determined using the disc diffusion assay, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) by serial dilution method. Also, free radical scavenging activity by 2,2-diphenyl-1-picrylhydrazyl (DPPH) was examined. Chemical composition was measured using the Gas Chromatography-Mass Spectrometry (GCMS). Results: The major constituents in T. polycephalum and T. lingulatum essential oils were 1,8- cineole and camphor, respectively. The highest sensitivity (MIC of 0.312 μg mL- ( was observed with T. polycephalum against Bacillus subtilis. The lowest IC50 (most potent radical scavenging activity) belonged to T. lingulatum essential oil. Pseudomonas aeruginosa and Streptococcus pyogenes showed resistance to T. lingulatum essential oil. Conclusion: The essential oil of T. polycephalum and T. lingulatum are potential natural antibacterials to treat human pathogenic bacteria and can be used as alternatives to produce antimicrobial agents.
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spelling doaj-art-088b34d17fa848d5955205255677ae6c2025-08-20T02:16:06ZengPasteur Institute of IranJournal of Medical Microbiology and Infectious Diseases2345-53492345-53302022-03-01101242910.52547/JoMMID.10.1.24Antioxidant and Antibacterial Activity of Tanacetum spp. Essential Oil and Chemical ComponentsMostafa Alamholo10https://orcid.org/0000-0003-1644-81791Department of Biotechnology, Institute of Science and Modern Technology, Rojava University, Qamishlo, SyriaIntroduction: The members of the genus Tanacetum are important medicinal plants. This study investigated the chemical composition and antibacterial activity of Tanacetum lingulatum and Tanacetum polycephalum essential oils on human infectious bacteria. Methods: The aerial part of two plants were collected from Urmia Province, Iran. The essential oils were extracted using a Clevenger device. The antibacterial effect of essential oils was determined using the disc diffusion assay, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) by serial dilution method. Also, free radical scavenging activity by 2,2-diphenyl-1-picrylhydrazyl (DPPH) was examined. Chemical composition was measured using the Gas Chromatography-Mass Spectrometry (GCMS). Results: The major constituents in T. polycephalum and T. lingulatum essential oils were 1,8- cineole and camphor, respectively. The highest sensitivity (MIC of 0.312 μg mL- ( was observed with T. polycephalum against Bacillus subtilis. The lowest IC50 (most potent radical scavenging activity) belonged to T. lingulatum essential oil. Pseudomonas aeruginosa and Streptococcus pyogenes showed resistance to T. lingulatum essential oil. Conclusion: The essential oil of T. polycephalum and T. lingulatum are potential natural antibacterials to treat human pathogenic bacteria and can be used as alternatives to produce antimicrobial agents.https://jommid.pasteur.ac.ir/article-1-356-en.htmltanacetum genusinfectious bacteriaphytochemical
spellingShingle Mostafa Alamholo1
Antioxidant and Antibacterial Activity of Tanacetum spp. Essential Oil and Chemical Components
Journal of Medical Microbiology and Infectious Diseases
tanacetum genus
infectious bacteria
phytochemical
title Antioxidant and Antibacterial Activity of Tanacetum spp. Essential Oil and Chemical Components
title_full Antioxidant and Antibacterial Activity of Tanacetum spp. Essential Oil and Chemical Components
title_fullStr Antioxidant and Antibacterial Activity of Tanacetum spp. Essential Oil and Chemical Components
title_full_unstemmed Antioxidant and Antibacterial Activity of Tanacetum spp. Essential Oil and Chemical Components
title_short Antioxidant and Antibacterial Activity of Tanacetum spp. Essential Oil and Chemical Components
title_sort antioxidant and antibacterial activity of tanacetum spp essential oil and chemical components
topic tanacetum genus
infectious bacteria
phytochemical
url https://jommid.pasteur.ac.ir/article-1-356-en.html
work_keys_str_mv AT mostafaalamholo1 antioxidantandantibacterialactivityoftanacetumsppessentialoilandchemicalcomponents