In Vitro CO-Releasing and Antioxidant Properties of Sulfonamide-Based CAI-CORMs in a H<sub>2</sub>O<sub>2</sub>-Stimulated Human Achilles Tendon-Derived Cell Model

In Vitro CO-Releasing and Antioxidant Properties of Sulfonamide-Based CAI-CORMs in a H<sub>2</sub>O<sub>2</sub>-Stimulated Human Achilles Tendon-Derived Cell Model

Tendinopathy is often described as a complex and multifactorial condition which affects tendons. Tendon disorders are marked by a reduction in mechanical function, accompanied by pain and swelling. At the molecular level, tendinopathy leads to oxidative stress-driven inflammation, increased cell dea...

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Bibliographic Details
Main Authors: Emanuela Berrino, Paolo Guglielmi, Fabrizio Carta, Simone Carradori, Cristina Campestre, Andrea Angeli, Francesca Arrighi, Virginia Pontecorvi, Paola Chimenti, Daniela Secci, Claudiu T. Supuran, Marialucia Gallorini
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Molecules
Subjects:
carbonic anhydrase inhibitors
CORMs
CO release
myoglobin
spectrophotometric assay
molecular hybrids
Online Access:https://www.mdpi.com/1420-3049/30/3/593
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