Histological and Immunohistochemical Characterization of a Case of Endometriosis in a Guinea Pig (Cavia tschudii)
Endometriosis is a chronic gynecological disease characterized by the ectopic proliferation of endometrial tissue outside of the uterine cavity. The pathogenesis of this disease is still obscure, and Sampson’s theory of retrograde menstruation is still the most widely accepted explanation. Endometri...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Veterinary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2017/4594510 |
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| author | Alfonso Baldi Andrea Lanza Francesco Menicagli Pietro G. Signorile Enrico P. Spugnini |
| author_facet | Alfonso Baldi Andrea Lanza Francesco Menicagli Pietro G. Signorile Enrico P. Spugnini |
| author_sort | Alfonso Baldi |
| collection | DOAJ |
| description | Endometriosis is a chronic gynecological disease characterized by the ectopic proliferation of endometrial tissue outside of the uterine cavity. The pathogenesis of this disease is still obscure, and Sampson’s theory of retrograde menstruation is still the most widely accepted explanation. Endometriosis in animals has been so far described not only in baboons and a rhesus macaque but also in dogs and horses that are nonmenstruating animals. In this article, we report the histological and immunohistochemical characterization of the first case of ovarian cystic endometriosis and adenomyosis in a guinea pig. The case presented supports the hypothesis that endometriosis is a disease not at all related to the phenomenon of retrograde menstruation but is a consequence of some alterations in the morphogenesis of the female genital system and therefore it could be found in any mammal. We suggest considering endometriosis among the other pathological phenotypes in animals displaying ovarian and uterine alterations and having a history of difficulties in conceiving. |
| format | Article |
| id | doaj-art-0888aa66af4249028325a1b12bba1d3c |
| institution | Kabale University |
| issn | 2090-7001 2090-701X |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Veterinary Medicine |
| spelling | doaj-art-0888aa66af4249028325a1b12bba1d3c2025-02-03T06:10:49ZengWileyCase Reports in Veterinary Medicine2090-70012090-701X2017-01-01201710.1155/2017/45945104594510Histological and Immunohistochemical Characterization of a Case of Endometriosis in a Guinea Pig (Cavia tschudii)Alfonso Baldi0Andrea Lanza1Francesco Menicagli2Pietro G. Signorile3Enrico P. Spugnini4Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Caserta, ItalyCentro Veterinario Gianicolense, Rome, ItalyCentro Veterinario Gianicolense, Rome, ItalyFondazione Italiana Endometriosi, Rome, ItalySAFU, Regina Elena Cancer Institute, Rome, ItalyEndometriosis is a chronic gynecological disease characterized by the ectopic proliferation of endometrial tissue outside of the uterine cavity. The pathogenesis of this disease is still obscure, and Sampson’s theory of retrograde menstruation is still the most widely accepted explanation. Endometriosis in animals has been so far described not only in baboons and a rhesus macaque but also in dogs and horses that are nonmenstruating animals. In this article, we report the histological and immunohistochemical characterization of the first case of ovarian cystic endometriosis and adenomyosis in a guinea pig. The case presented supports the hypothesis that endometriosis is a disease not at all related to the phenomenon of retrograde menstruation but is a consequence of some alterations in the morphogenesis of the female genital system and therefore it could be found in any mammal. We suggest considering endometriosis among the other pathological phenotypes in animals displaying ovarian and uterine alterations and having a history of difficulties in conceiving.http://dx.doi.org/10.1155/2017/4594510 |
| spellingShingle | Alfonso Baldi Andrea Lanza Francesco Menicagli Pietro G. Signorile Enrico P. Spugnini Histological and Immunohistochemical Characterization of a Case of Endometriosis in a Guinea Pig (Cavia tschudii) Case Reports in Veterinary Medicine |
| title | Histological and Immunohistochemical Characterization of a Case of Endometriosis in a Guinea Pig (Cavia tschudii) |
| title_full | Histological and Immunohistochemical Characterization of a Case of Endometriosis in a Guinea Pig (Cavia tschudii) |
| title_fullStr | Histological and Immunohistochemical Characterization of a Case of Endometriosis in a Guinea Pig (Cavia tschudii) |
| title_full_unstemmed | Histological and Immunohistochemical Characterization of a Case of Endometriosis in a Guinea Pig (Cavia tschudii) |
| title_short | Histological and Immunohistochemical Characterization of a Case of Endometriosis in a Guinea Pig (Cavia tschudii) |
| title_sort | histological and immunohistochemical characterization of a case of endometriosis in a guinea pig cavia tschudii |
| url | http://dx.doi.org/10.1155/2017/4594510 |
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