Ischemic Stroke during Pregnancy and Puerperium

Ischemic stroke during pregnancy and puerperium represents a rare occurrence but it could be a serious and stressful event for mothers, infants, and also families. Whenever it does occur, many concerns arise about the safety of the mother and the fetus in relation to common diagnostic tests and the...

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Main Authors: Elisabetta Del Zotto, Alessia Giossi, Irene Volonghi, Paolo Costa, Alessandro Padovani, Alessandro Pezzini
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Stroke Research and Treatment
Online Access:http://dx.doi.org/10.4061/2011/606780
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author Elisabetta Del Zotto
Alessia Giossi
Irene Volonghi
Paolo Costa
Alessandro Padovani
Alessandro Pezzini
author_facet Elisabetta Del Zotto
Alessia Giossi
Irene Volonghi
Paolo Costa
Alessandro Padovani
Alessandro Pezzini
author_sort Elisabetta Del Zotto
collection DOAJ
description Ischemic stroke during pregnancy and puerperium represents a rare occurrence but it could be a serious and stressful event for mothers, infants, and also families. Whenever it does occur, many concerns arise about the safety of the mother and the fetus in relation to common diagnostic tests and therapies leading to a more conservative approach. The physiological adaptations in the cardiovascular system and in the coagulability that accompany the pregnant state, which are more significant around delivery and in the postpartum period, likely contribute to increasing the risk of an ischemic stroke. Most of the causes of an ischemic stroke in the young may also occur in pregnant patients. Despite this, there are specific conditions related to pregnancy which may be considered when assessing this particular group of patients such as pre-eclampsia-eclampsia, choriocarcinoma, peripartum cardiomiopathy, amniotic fluid embolization, and postpartum cerebral angiopathy. This article will consider several questions related to pregnancy-associated ischemic stroke, dwelling on epidemiological and specific etiological aspects, diagnostic issue concerning the use of neuroimaging, and the related potential risks to the embryo and fetus. Therapeutic issues surrounding the use of anticoagulant and antiplatelets agents will be discussed along with the few available reports regarding the use of thrombolytic therapy during pregnancy.
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issn 2042-0056
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series Stroke Research and Treatment
spelling doaj-art-0885a691cc934914a53300a5aa1d17382025-08-20T03:55:32ZengWileyStroke Research and Treatment2042-00562011-01-01201110.4061/2011/606780606780Ischemic Stroke during Pregnancy and PuerperiumElisabetta Del Zotto0Alessia Giossi1Irene Volonghi2Paolo Costa3Alessandro Padovani4Alessandro Pezzini5Dipartimento di Scienze Biomediche e Biotecnologie, Università degli Studi di Brescia, 25128 Brescia, ItalyDipartimento di Scienze Biomediche e Biotecnologie, Università degli Studi di Brescia, 25128 Brescia, ItalyDipartimento di Scienze Biomediche e Biotecnologie, Università degli Studi di Brescia, 25128 Brescia, ItalyDipartimento di Scienze Biomediche e Biotecnologie, Università degli Studi di Brescia, 25128 Brescia, ItalyDipartimento di Scienze Biomediche e Biotecnologie, Università degli Studi di Brescia, 25128 Brescia, ItalyDipartimento di Scienze Biomediche e Biotecnologie, Università degli Studi di Brescia, 25128 Brescia, ItalyIschemic stroke during pregnancy and puerperium represents a rare occurrence but it could be a serious and stressful event for mothers, infants, and also families. Whenever it does occur, many concerns arise about the safety of the mother and the fetus in relation to common diagnostic tests and therapies leading to a more conservative approach. The physiological adaptations in the cardiovascular system and in the coagulability that accompany the pregnant state, which are more significant around delivery and in the postpartum period, likely contribute to increasing the risk of an ischemic stroke. Most of the causes of an ischemic stroke in the young may also occur in pregnant patients. Despite this, there are specific conditions related to pregnancy which may be considered when assessing this particular group of patients such as pre-eclampsia-eclampsia, choriocarcinoma, peripartum cardiomiopathy, amniotic fluid embolization, and postpartum cerebral angiopathy. This article will consider several questions related to pregnancy-associated ischemic stroke, dwelling on epidemiological and specific etiological aspects, diagnostic issue concerning the use of neuroimaging, and the related potential risks to the embryo and fetus. Therapeutic issues surrounding the use of anticoagulant and antiplatelets agents will be discussed along with the few available reports regarding the use of thrombolytic therapy during pregnancy.http://dx.doi.org/10.4061/2011/606780
spellingShingle Elisabetta Del Zotto
Alessia Giossi
Irene Volonghi
Paolo Costa
Alessandro Padovani
Alessandro Pezzini
Ischemic Stroke during Pregnancy and Puerperium
Stroke Research and Treatment
title Ischemic Stroke during Pregnancy and Puerperium
title_full Ischemic Stroke during Pregnancy and Puerperium
title_fullStr Ischemic Stroke during Pregnancy and Puerperium
title_full_unstemmed Ischemic Stroke during Pregnancy and Puerperium
title_short Ischemic Stroke during Pregnancy and Puerperium
title_sort ischemic stroke during pregnancy and puerperium
url http://dx.doi.org/10.4061/2011/606780
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AT alessiagiossi ischemicstrokeduringpregnancyandpuerperium
AT irenevolonghi ischemicstrokeduringpregnancyandpuerperium
AT paolocosta ischemicstrokeduringpregnancyandpuerperium
AT alessandropadovani ischemicstrokeduringpregnancyandpuerperium
AT alessandropezzini ischemicstrokeduringpregnancyandpuerperium