From door to diagnosis: A case report of a rare and life-threatening presentation of Takayasu arteritis
Takayasu arteritis is a chronic, large vessel vasculitis that typically affects the aorta and its main branches. We present a case of a 33-year-old male patient who was diagnosed with Takayasu arteritis after being admitted for acute cardiogenic shock requiring inotropes. Initial transthoracic echoc...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2025-04-01
|
| Series: | SAGE Open Medical Case Reports |
| Online Access: | https://doi.org/10.1177/2050313X251335205 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850196574085316608 |
|---|---|
| author | Eiad Habib Laura MacPhee Fawad Aslam Bhavesh Patel Ayan Sen Lisa LeMond Ina Soh Chelsea Marshall Marie Grill Kartik Mangipudi Nolan McBride Hiroshi Sekiguchi |
| author_facet | Eiad Habib Laura MacPhee Fawad Aslam Bhavesh Patel Ayan Sen Lisa LeMond Ina Soh Chelsea Marshall Marie Grill Kartik Mangipudi Nolan McBride Hiroshi Sekiguchi |
| author_sort | Eiad Habib |
| collection | DOAJ |
| description | Takayasu arteritis is a chronic, large vessel vasculitis that typically affects the aorta and its main branches. We present a case of a 33-year-old male patient who was diagnosed with Takayasu arteritis after being admitted for acute cardiogenic shock requiring inotropes. Initial transthoracic echocardiography demonstrated severe biventricular dysfunction. Computed tomography imaging of his chest showed pulmonary infarcts. Patient subsequently developed sudden lower extremity weakness and bowel incontinence, and urgent magnetic resonance imaging of his spine demonstrated thoracolumbar vascular myelopathy. Transesophageal echocardiography revealed diffuse symmetrical thickening of the walls of the aorta; findings suggestive of aortitis. Patient was initiated on intravenous corticosteroid and systemic anticoagulation. Subsequent computed tomography angiography demonstrated irregular luminal contour of the aortic arch, and complete occlusion of the left subclavian artery, abdominal aorta, superior mesenteric artery, and left renal artery. He underwent an emergent aortoiliac thrombectomy. He was transitioned to oral prednisone, tocilizumab, and azathioprine with excellent recovery. |
| format | Article |
| id | doaj-art-08816dea26f44c3bba0b50c9e2a65fb1 |
| institution | OA Journals |
| issn | 2050-313X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | SAGE Open Medical Case Reports |
| spelling | doaj-art-08816dea26f44c3bba0b50c9e2a65fb12025-08-20T02:13:26ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2025-04-011310.1177/2050313X251335205From door to diagnosis: A case report of a rare and life-threatening presentation of Takayasu arteritisEiad Habib0Laura MacPhee1Fawad Aslam2Bhavesh Patel3Ayan Sen4Lisa LeMond5Ina Soh6Chelsea Marshall7Marie Grill8Kartik Mangipudi9Nolan McBride10Hiroshi Sekiguchi11Department of Cardiovascular Medicine, Mayo Clinic Hospital, Phoenix, AZ, USADepartment of Critical Care Medicine, Mayo Clinic Hospital, Phoenix, AZ, USADepartment of Rheumatology, Mayo Clinic Hospital, Phoenix, AZ, USADepartment of Critical Care Medicine, Mayo Clinic Hospital, Phoenix, AZ, USADepartment of Critical Care Medicine, Mayo Clinic Hospital, Phoenix, AZ, USADepartment of Cardiovascular Medicine, Mayo Clinic Hospital, Phoenix, AZ, USADepartment of Vascular Surgery, Mayo Clinic Hospital, Phoenix, AZ, USADepartment of Cardiovascular Medicine, Honor Health, Phoenix, AZ, USADepartment of Neurology, Mayo Clinic Hospital, Phoenix, AZ, USADepartment of Neurology, University of Florida, Jacksonville, FL, USADepartment of Rheumatology, Mayo Clinic Hospital, Phoenix, AZ, USADepartment of Critical Care Medicine, Mayo Clinic Hospital, Phoenix, AZ, USATakayasu arteritis is a chronic, large vessel vasculitis that typically affects the aorta and its main branches. We present a case of a 33-year-old male patient who was diagnosed with Takayasu arteritis after being admitted for acute cardiogenic shock requiring inotropes. Initial transthoracic echocardiography demonstrated severe biventricular dysfunction. Computed tomography imaging of his chest showed pulmonary infarcts. Patient subsequently developed sudden lower extremity weakness and bowel incontinence, and urgent magnetic resonance imaging of his spine demonstrated thoracolumbar vascular myelopathy. Transesophageal echocardiography revealed diffuse symmetrical thickening of the walls of the aorta; findings suggestive of aortitis. Patient was initiated on intravenous corticosteroid and systemic anticoagulation. Subsequent computed tomography angiography demonstrated irregular luminal contour of the aortic arch, and complete occlusion of the left subclavian artery, abdominal aorta, superior mesenteric artery, and left renal artery. He underwent an emergent aortoiliac thrombectomy. He was transitioned to oral prednisone, tocilizumab, and azathioprine with excellent recovery.https://doi.org/10.1177/2050313X251335205 |
| spellingShingle | Eiad Habib Laura MacPhee Fawad Aslam Bhavesh Patel Ayan Sen Lisa LeMond Ina Soh Chelsea Marshall Marie Grill Kartik Mangipudi Nolan McBride Hiroshi Sekiguchi From door to diagnosis: A case report of a rare and life-threatening presentation of Takayasu arteritis SAGE Open Medical Case Reports |
| title | From door to diagnosis: A case report of a rare and life-threatening presentation of Takayasu arteritis |
| title_full | From door to diagnosis: A case report of a rare and life-threatening presentation of Takayasu arteritis |
| title_fullStr | From door to diagnosis: A case report of a rare and life-threatening presentation of Takayasu arteritis |
| title_full_unstemmed | From door to diagnosis: A case report of a rare and life-threatening presentation of Takayasu arteritis |
| title_short | From door to diagnosis: A case report of a rare and life-threatening presentation of Takayasu arteritis |
| title_sort | from door to diagnosis a case report of a rare and life threatening presentation of takayasu arteritis |
| url | https://doi.org/10.1177/2050313X251335205 |
| work_keys_str_mv | AT eiadhabib fromdoortodiagnosisacasereportofarareandlifethreateningpresentationoftakayasuarteritis AT lauramacphee fromdoortodiagnosisacasereportofarareandlifethreateningpresentationoftakayasuarteritis AT fawadaslam fromdoortodiagnosisacasereportofarareandlifethreateningpresentationoftakayasuarteritis AT bhaveshpatel fromdoortodiagnosisacasereportofarareandlifethreateningpresentationoftakayasuarteritis AT ayansen fromdoortodiagnosisacasereportofarareandlifethreateningpresentationoftakayasuarteritis AT lisalemond fromdoortodiagnosisacasereportofarareandlifethreateningpresentationoftakayasuarteritis AT inasoh fromdoortodiagnosisacasereportofarareandlifethreateningpresentationoftakayasuarteritis AT chelseamarshall fromdoortodiagnosisacasereportofarareandlifethreateningpresentationoftakayasuarteritis AT mariegrill fromdoortodiagnosisacasereportofarareandlifethreateningpresentationoftakayasuarteritis AT kartikmangipudi fromdoortodiagnosisacasereportofarareandlifethreateningpresentationoftakayasuarteritis AT nolanmcbride fromdoortodiagnosisacasereportofarareandlifethreateningpresentationoftakayasuarteritis AT hiroshisekiguchi fromdoortodiagnosisacasereportofarareandlifethreateningpresentationoftakayasuarteritis |