Evaluation of Antibiotics Residues in Milk and Meat Using Different Analytical Methods
Veterinary drugs are pharmacologically and biologically active chemical agents. At present, veterinary drugs are extensively used to prevent and treat animal diseases, to promote animal growth, and to improve the conversion rate of feed. However, the use of veterinary drugs in food-producing animals...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | International Journal of Analytical Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2023/4380261 |
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| author | Melaku Getahun Rahel Belete Abebe Ashenafi Kibret Sendekie Alem Endeshaw Woldeyohanis Asmamaw Emagn Kasahun |
| author_facet | Melaku Getahun Rahel Belete Abebe Ashenafi Kibret Sendekie Alem Endeshaw Woldeyohanis Asmamaw Emagn Kasahun |
| author_sort | Melaku Getahun |
| collection | DOAJ |
| description | Veterinary drugs are pharmacologically and biologically active chemical agents. At present, veterinary drugs are extensively used to prevent and treat animal diseases, to promote animal growth, and to improve the conversion rate of feed. However, the use of veterinary drugs in food-producing animals may leave residues of the parent compounds and/or their metabolites in food products resulting in harmful effects on humans. To ensure food safety, sensitive and effective analytical methods have been developing rapidly. This review describes sample extraction and cleanup methods, and different analytical techniques are used for the determination of veterinary drug residues in milk and meat. Sample extraction methods, such as solvent extraction, liquid-liquid extraction, and cleanup methods such as dispersive solid-phase extraction and immunoaffinity chromatography, were summarized. Different types of analytical methods such as microbial, immunological, biosensor, thin layer chromatography, high-performance liquid chromatography, and liquid chromatography–tandem mass spectrometry were discussed for the analysis of veterinary drug residues in animal-derived foods. Liquid chromatography–tandem mass spectrometry is the most widely used analytical technique for the determination of antibiotic drug residues. This is due to the powerful separation of LC and accurate identification of MS, and LC-MS/MS is more popular in the analysis of veterinary drug residues. |
| format | Article |
| id | doaj-art-08800d9197544a5fa8a82cc2989a6a9f |
| institution | OA Journals |
| issn | 1687-8779 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Analytical Chemistry |
| spelling | doaj-art-08800d9197544a5fa8a82cc2989a6a9f2025-08-20T02:01:34ZengWileyInternational Journal of Analytical Chemistry1687-87792023-01-01202310.1155/2023/4380261Evaluation of Antibiotics Residues in Milk and Meat Using Different Analytical MethodsMelaku Getahun0Rahel Belete Abebe1Ashenafi Kibret Sendekie2Alem Endeshaw Woldeyohanis3Asmamaw Emagn Kasahun4Department of Veterinary PharmacyDepartment of Clinical PharmacyDepartment of Clinical PharmacyDepartment of Pharmaceutics and Social PharmacyDepartment of Pharmaceutics and Social PharmacyVeterinary drugs are pharmacologically and biologically active chemical agents. At present, veterinary drugs are extensively used to prevent and treat animal diseases, to promote animal growth, and to improve the conversion rate of feed. However, the use of veterinary drugs in food-producing animals may leave residues of the parent compounds and/or their metabolites in food products resulting in harmful effects on humans. To ensure food safety, sensitive and effective analytical methods have been developing rapidly. This review describes sample extraction and cleanup methods, and different analytical techniques are used for the determination of veterinary drug residues in milk and meat. Sample extraction methods, such as solvent extraction, liquid-liquid extraction, and cleanup methods such as dispersive solid-phase extraction and immunoaffinity chromatography, were summarized. Different types of analytical methods such as microbial, immunological, biosensor, thin layer chromatography, high-performance liquid chromatography, and liquid chromatography–tandem mass spectrometry were discussed for the analysis of veterinary drug residues in animal-derived foods. Liquid chromatography–tandem mass spectrometry is the most widely used analytical technique for the determination of antibiotic drug residues. This is due to the powerful separation of LC and accurate identification of MS, and LC-MS/MS is more popular in the analysis of veterinary drug residues.http://dx.doi.org/10.1155/2023/4380261 |
| spellingShingle | Melaku Getahun Rahel Belete Abebe Ashenafi Kibret Sendekie Alem Endeshaw Woldeyohanis Asmamaw Emagn Kasahun Evaluation of Antibiotics Residues in Milk and Meat Using Different Analytical Methods International Journal of Analytical Chemistry |
| title | Evaluation of Antibiotics Residues in Milk and Meat Using Different Analytical Methods |
| title_full | Evaluation of Antibiotics Residues in Milk and Meat Using Different Analytical Methods |
| title_fullStr | Evaluation of Antibiotics Residues in Milk and Meat Using Different Analytical Methods |
| title_full_unstemmed | Evaluation of Antibiotics Residues in Milk and Meat Using Different Analytical Methods |
| title_short | Evaluation of Antibiotics Residues in Milk and Meat Using Different Analytical Methods |
| title_sort | evaluation of antibiotics residues in milk and meat using different analytical methods |
| url | http://dx.doi.org/10.1155/2023/4380261 |
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