New Allyl Derivative of Curcumin: Synthesis and Crystal Structure of (1<i>E</i>,6<i>E</i>)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione
A new allyl derivative of curcumin containing three allyl groups (1<i>E</i>,6<i>E</i>)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione was synthesized by the reaction of curcumin with the excess of allyl bromide in the presence of K<sub>2</sub&...
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2024-10-01
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| author | Anna A. Druzina Olga B. Zhidkova Sergey A. Anufriev Ekaterina V. Dubasova Ivan V. Ananyev Samya Banerjee Igor B. Sivaev Vladimir I. Bregadze |
| author_facet | Anna A. Druzina Olga B. Zhidkova Sergey A. Anufriev Ekaterina V. Dubasova Ivan V. Ananyev Samya Banerjee Igor B. Sivaev Vladimir I. Bregadze |
| author_sort | Anna A. Druzina |
| collection | DOAJ |
| description | A new allyl derivative of curcumin containing three allyl groups (1<i>E</i>,6<i>E</i>)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione was synthesized by the reaction of curcumin with the excess of allyl bromide in the presence of K<sub>2</sub>CO<sub>3</sub> in acetone under reflux. The triple-allylated curcumin was characterized by <sup>1</sup>H and <sup>13</sup>C-NMR spectroscopy and single-crystal X-ray diffraction analysis. |
| format | Article |
| id | doaj-art-087ca5d4efe3434db935bd8e890a0eb2 |
| institution | OA Journals |
| issn | 1422-8599 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molbank |
| spelling | doaj-art-087ca5d4efe3434db935bd8e890a0eb22025-08-20T02:01:15ZengMDPI AGMolbank1422-85992024-10-0120244M190510.3390/M1905New Allyl Derivative of Curcumin: Synthesis and Crystal Structure of (1<i>E</i>,6<i>E</i>)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dioneAnna A. Druzina0Olga B. Zhidkova1Sergey A. Anufriev2Ekaterina V. Dubasova3Ivan V. Ananyev4Samya Banerjee5Igor B. Sivaev6Vladimir I. Bregadze7A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Str., 119991 Moscow, RussiaA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Str., 119991 Moscow, RussiaA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Str., 119991 Moscow, RussiaN.S. Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, 31 Leninsky Avenue, 119991 Moscow, RussiaA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Str., 119991 Moscow, RussiaDepartment of Chemistry, Indian Institute of Technology (BHU), Varanasi 221005, UP, IndiaA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Str., 119991 Moscow, RussiaA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Str., 119991 Moscow, RussiaA new allyl derivative of curcumin containing three allyl groups (1<i>E</i>,6<i>E</i>)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione was synthesized by the reaction of curcumin with the excess of allyl bromide in the presence of K<sub>2</sub>CO<sub>3</sub> in acetone under reflux. The triple-allylated curcumin was characterized by <sup>1</sup>H and <sup>13</sup>C-NMR spectroscopy and single-crystal X-ray diffraction analysis.https://www.mdpi.com/1422-8599/2024/4/M1905curcuminallyl derivativesynthesisNMR spectrasingle-crystal X-ray diffraction |
| spellingShingle | Anna A. Druzina Olga B. Zhidkova Sergey A. Anufriev Ekaterina V. Dubasova Ivan V. Ananyev Samya Banerjee Igor B. Sivaev Vladimir I. Bregadze New Allyl Derivative of Curcumin: Synthesis and Crystal Structure of (1<i>E</i>,6<i>E</i>)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione Molbank curcumin allyl derivative synthesis NMR spectra single-crystal X-ray diffraction |
| title | New Allyl Derivative of Curcumin: Synthesis and Crystal Structure of (1<i>E</i>,6<i>E</i>)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione |
| title_full | New Allyl Derivative of Curcumin: Synthesis and Crystal Structure of (1<i>E</i>,6<i>E</i>)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione |
| title_fullStr | New Allyl Derivative of Curcumin: Synthesis and Crystal Structure of (1<i>E</i>,6<i>E</i>)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione |
| title_full_unstemmed | New Allyl Derivative of Curcumin: Synthesis and Crystal Structure of (1<i>E</i>,6<i>E</i>)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione |
| title_short | New Allyl Derivative of Curcumin: Synthesis and Crystal Structure of (1<i>E</i>,6<i>E</i>)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione |
| title_sort | new allyl derivative of curcumin synthesis and crystal structure of 1 i e i 6 i e i 4 allyl 1 7 bis 4 allyloxy 3 methoxyphenyl hepta 1 6 diene 3 5 dione |
| topic | curcumin allyl derivative synthesis NMR spectra single-crystal X-ray diffraction |
| url | https://www.mdpi.com/1422-8599/2024/4/M1905 |
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