Marburg virus: an emerging global threat
Marburg virus disease is a rare, but severe illness caused by highly pathogenic Marburg virus, a member of the Filoviridae family. The virus was first identified in 1967 in Marburg and Frankfurt, Germany, as well as Belgrade, Serbia. Since then, sporadic outbreaks have been reported in Central an...
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| Format: | Article |
| Language: | English |
| Published: |
University of Tabriz
2024-09-01
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| Series: | Journal of Zoonotic Diseases |
| Subjects: | |
| Online Access: | https://jzd.tabrizu.ac.ir/article_18312.html |
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| Summary: | Marburg virus disease is a rare, but severe illness caused by highly
pathogenic Marburg virus, a member of the Filoviridae family. The virus was first
identified in 1967 in Marburg and Frankfurt, Germany, as well as Belgrade, Serbia.
Since then, sporadic outbreaks have been reported in Central and East Africa. The
fruit bats of the genus Rousettus are the major reservoir for the virus. The largest
recorded outbreak occurred in Angola in 2005, with 374 cases and 329 deaths,
resulting in a mortality rate of approximately 88%, underscoring this virus's potential
for causing a devastating impact. Historically, the Marburg virus has received less
attention compared to the Ebola virus. However, the geographical expansion of this
virus in new regions such as Guinea, Equatorial Guinea, Ghana, and Tanzania
highlights its growing threat. The sporadic outbreaks of this deadly pathogen
necessitate continued investment in research, surveillance, and public health
preparedness to mitigate the impact of this virus on global health security. This
review is intended to provide an overview of our current knowledge of the Marburg
virus, which is crucial for the development of Marburg virus countermeasures.
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| ISSN: | 2717-2910 |