Comparison of Infection and Urosepsis Rates of Ciprofloxacin and Ceftriaxone Prophylaxis before Percutaneous Nephrolithotomy: A Prospective and Randomised Study
This study aimed at determining the choice and administration duration of ideal antibiotic prophylaxis before percutaneous nephrolithotomy (PNL) operation, a treatment modality for nephrolithiasis. The study included 90 patients who had no internal problem, yet had a negative urine culture and under...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/916381 |
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| author | Abdullah Demirtas Yunus Emre Yildirim Mustafa Sofikerim Esma Gunduz Kaya Emre Can Akinsal Sevket Tolga Tombul Oguz Ekmekcioglu Ibrahim Gulmez |
| author_facet | Abdullah Demirtas Yunus Emre Yildirim Mustafa Sofikerim Esma Gunduz Kaya Emre Can Akinsal Sevket Tolga Tombul Oguz Ekmekcioglu Ibrahim Gulmez |
| author_sort | Abdullah Demirtas |
| collection | DOAJ |
| description | This study aimed at determining the choice and administration duration of ideal antibiotic prophylaxis before percutaneous nephrolithotomy (PNL) operation, a treatment modality for nephrolithiasis. The study included 90 patients who had no internal problem, yet had a negative urine culture and underwent a PNL operation. We compared infection rates between ciprofloxacin and ceftriaxone groups and their subgroups. The results showed no statistical difference between ciprofloxacin and ceftriaxone groups in terms of systemic inflammatory response syndrome (SIRS) (CIPP=0.306, CTX P=0.334. As a result of this study no statistical difference was observed between ciprofloxacin and ceftriaxone in terms of SIRS. It seems, however, reasonable to choose ceftriaxone, considering antibiotic sensitivity of microorganisms and detection of three cases accepted as urosepsis in the ciprofloxacin group. As there is no difference between short, and long-term prophylactic use of these antibiotics, preference of short-term prophylaxis for patients with no risk of infection will be important to avoid inappropriate antibiotic usage. |
| format | Article |
| id | doaj-art-08776374163c42e594bcb4ef3c1adeff |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-08776374163c42e594bcb4ef3c1adeff2025-08-20T03:55:32ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/916381916381Comparison of Infection and Urosepsis Rates of Ciprofloxacin and Ceftriaxone Prophylaxis before Percutaneous Nephrolithotomy: A Prospective and Randomised StudyAbdullah Demirtas0Yunus Emre Yildirim1Mustafa Sofikerim2Esma Gunduz Kaya3Emre Can Akinsal4Sevket Tolga Tombul5Oguz Ekmekcioglu6Ibrahim Gulmez7Department of Urology, Erciyes University Medical Faculty, 38039 Kayseri, TurkeyDepartment of Urology, Erciyes University Medical Faculty, 38039 Kayseri, TurkeyDepartment of Urology, Acıbadem University Medical Faculty, 34848 İstanbul, TurkeyDepartment of Microbiology, Erciyes University Medical Faculty, 38039 Kayseri, TurkeyDepartment of Urology, Erciyes University Medical Faculty, 38039 Kayseri, TurkeyDepartment of Urology, Erciyes University Medical Faculty, 38039 Kayseri, TurkeyDepartment of Urology, Erciyes University Medical Faculty, 38039 Kayseri, TurkeyDepartment of Urology, Erciyes University Medical Faculty, 38039 Kayseri, TurkeyThis study aimed at determining the choice and administration duration of ideal antibiotic prophylaxis before percutaneous nephrolithotomy (PNL) operation, a treatment modality for nephrolithiasis. The study included 90 patients who had no internal problem, yet had a negative urine culture and underwent a PNL operation. We compared infection rates between ciprofloxacin and ceftriaxone groups and their subgroups. The results showed no statistical difference between ciprofloxacin and ceftriaxone groups in terms of systemic inflammatory response syndrome (SIRS) (CIPP=0.306, CTX P=0.334. As a result of this study no statistical difference was observed between ciprofloxacin and ceftriaxone in terms of SIRS. It seems, however, reasonable to choose ceftriaxone, considering antibiotic sensitivity of microorganisms and detection of three cases accepted as urosepsis in the ciprofloxacin group. As there is no difference between short, and long-term prophylactic use of these antibiotics, preference of short-term prophylaxis for patients with no risk of infection will be important to avoid inappropriate antibiotic usage.http://dx.doi.org/10.1100/2012/916381 |
| spellingShingle | Abdullah Demirtas Yunus Emre Yildirim Mustafa Sofikerim Esma Gunduz Kaya Emre Can Akinsal Sevket Tolga Tombul Oguz Ekmekcioglu Ibrahim Gulmez Comparison of Infection and Urosepsis Rates of Ciprofloxacin and Ceftriaxone Prophylaxis before Percutaneous Nephrolithotomy: A Prospective and Randomised Study The Scientific World Journal |
| title | Comparison of Infection and Urosepsis Rates of Ciprofloxacin and Ceftriaxone Prophylaxis before Percutaneous Nephrolithotomy: A Prospective and Randomised Study |
| title_full | Comparison of Infection and Urosepsis Rates of Ciprofloxacin and Ceftriaxone Prophylaxis before Percutaneous Nephrolithotomy: A Prospective and Randomised Study |
| title_fullStr | Comparison of Infection and Urosepsis Rates of Ciprofloxacin and Ceftriaxone Prophylaxis before Percutaneous Nephrolithotomy: A Prospective and Randomised Study |
| title_full_unstemmed | Comparison of Infection and Urosepsis Rates of Ciprofloxacin and Ceftriaxone Prophylaxis before Percutaneous Nephrolithotomy: A Prospective and Randomised Study |
| title_short | Comparison of Infection and Urosepsis Rates of Ciprofloxacin and Ceftriaxone Prophylaxis before Percutaneous Nephrolithotomy: A Prospective and Randomised Study |
| title_sort | comparison of infection and urosepsis rates of ciprofloxacin and ceftriaxone prophylaxis before percutaneous nephrolithotomy a prospective and randomised study |
| url | http://dx.doi.org/10.1100/2012/916381 |
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