Paternally expressed, imprinted insulin-like growth factor-2 in chorionic villi correlates significantly with birth weight.

Paternally expressed, imprinted insulin-like growth factor-2 in chorionic villi correlates significantly with birth weight.

<h4>Context</h4>Fetal growth involves highly complex molecular pathways. IGF2 is a key paternally expressed growth hormone that is critical for in utero growth in mice. Its role in human fetal growth has remained ambiguous, as it has only been studied in term tissues. Conversely the mate...

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Main Authors: Charalambos Demetriou, Sayeda Abu-Amero, Anna C Thomas, Miho Ishida, Reena Aggarwal, Lara Al-Olabi, Lydia J Leon, Jaime L Stafford, Argyro Syngelaki, Donald Peebles, Kypros H Nicolaides, Lesley Regan, Philip Stanier, Gudrun E Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0085454
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