Serum glial fibrillary protein reflects early brain injury dynamics and cognitive changes after deep brain stimulation surgery

Serum glial fibrillary protein reflects early brain injury dynamics and cognitive changes after deep brain stimulation surgery

Abstract Deep brain stimulation (DBS) is an efficient treatment for movement disorders, most commonly Parkinson’s Disease (PD), dystonia and essential tremor. DBS surgery carries risks, e.g. the risk of delayed peri-lead edema (PLE) and the risk of postoperative cognitive decline. The mechanisms of...

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Main Authors: Anika Frank, Jonas Arjomand, Jonas Bendig, Mia Delfs, Lisa Klingelhoefer, Witold H. Polanski, Katja Akgün, Tjalf Ziemssen, Björn Falkenburger, Nils Schnalke
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Parkinson’s Disease
Dystonia
Tremor
DBS
sNfL
sGFAP
Online Access:https://doi.org/10.1038/s41598-025-00399-3
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https://doi.org/10.1038/s41598-025-00399-3

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