Implications of the <i>STAT5B</i> and <i>C1QBP</i> Genes of Grain Aphid <i>Sitobion avenae</i> in the Transmission of Barley Yellow Dwarf Virus

Many plant viruses are transmitted by insect vectors, and the transmission process is regulated by key genes within the vector. However, few of these genes have been reported. Previous studies in our laboratory have shown that the expression of the signal transducer and activator of transcription 5B...

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Main Authors: Chiping Liu, Manwen Zhang, Chen Luo, Zuqing Hu
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Agronomy
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Online Access:https://www.mdpi.com/2073-4395/14/12/2787
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author Chiping Liu
Manwen Zhang
Chen Luo
Zuqing Hu
author_facet Chiping Liu
Manwen Zhang
Chen Luo
Zuqing Hu
author_sort Chiping Liu
collection DOAJ
description Many plant viruses are transmitted by insect vectors, and the transmission process is regulated by key genes within the vector. However, few of these genes have been reported. Previous studies in our laboratory have shown that the expression of the signal transducer and activator of transcription 5B (<i>STAT5B</i>) in viruliferous vector aphids carrying barley yellow dwarf virus (BYDV) was upregulated, and the complement component 1 Q subcomponent binding protein (C1QBP) within the aphid interacted with the coat protein (CP) and aphid transmission protein (ATP) of BYDV. In this study, we examined the expression levels of <i>STAT5B</i> and <i>C1QBP</i> in the vector aphid <i>Sitobion avenae</i> (Fabricius) (Hemiptera: Aphididae) using the qPCR method. We conducted this analysis during the acquisition accession periods (AAPs) and inoculation accession periods (IAPs) of the BYDV species GAV (BYDV-GAV). Furthermore, the effects of <i>STAT5B</i> and <i>C1QBP</i> on the acquisition, retention, and transmission of BYDV-GAV in <i>S. avenae</i> were verified using the RNA interference (RNAi) method. The results show the following: (1) the expression levels of <i>STAT5B</i> and <i>C1QBP</i> were significantly upregulated during the AAPs and IAPs of BYDV-GAV; (2) the silencing of <i>STAT5B</i> led to a significant increase in BYDV-GAV retention during IAPs; and (3) the silencing of <i>C1QBP</i> resulted in a notable decrease in BYDV-GAV acquisition during the AAPs, as well as a significant increase in BYDV-GAV retention during the IAPs. These results suggest that <i>STAT5B</i> and <i>C1QBP</i> in <i>S. avenae</i> play a role in BYDV-GAV transmission. These findings highlight the functions of the <i>STAT5B</i> and <i>C1QBP</i> genes and identify <i>C1QBP</i> as a potential target gene for further RNAi-based studies to control the transmission of BYDV-GAV.
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spelling doaj-art-084fdb5ad0244ebcbde8e866d4e05df62025-08-20T02:53:30ZengMDPI AGAgronomy2073-43952024-11-011412278710.3390/agronomy14122787Implications of the <i>STAT5B</i> and <i>C1QBP</i> Genes of Grain Aphid <i>Sitobion avenae</i> in the Transmission of Barley Yellow Dwarf VirusChiping Liu0Manwen Zhang1Chen Luo2Zuqing Hu3State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Key Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on the Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling 712100, ChinaState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Key Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on the Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling 712100, ChinaState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Key Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on the Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling 712100, ChinaState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, Key Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on the Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling 712100, ChinaMany plant viruses are transmitted by insect vectors, and the transmission process is regulated by key genes within the vector. However, few of these genes have been reported. Previous studies in our laboratory have shown that the expression of the signal transducer and activator of transcription 5B (<i>STAT5B</i>) in viruliferous vector aphids carrying barley yellow dwarf virus (BYDV) was upregulated, and the complement component 1 Q subcomponent binding protein (C1QBP) within the aphid interacted with the coat protein (CP) and aphid transmission protein (ATP) of BYDV. In this study, we examined the expression levels of <i>STAT5B</i> and <i>C1QBP</i> in the vector aphid <i>Sitobion avenae</i> (Fabricius) (Hemiptera: Aphididae) using the qPCR method. We conducted this analysis during the acquisition accession periods (AAPs) and inoculation accession periods (IAPs) of the BYDV species GAV (BYDV-GAV). Furthermore, the effects of <i>STAT5B</i> and <i>C1QBP</i> on the acquisition, retention, and transmission of BYDV-GAV in <i>S. avenae</i> were verified using the RNA interference (RNAi) method. The results show the following: (1) the expression levels of <i>STAT5B</i> and <i>C1QBP</i> were significantly upregulated during the AAPs and IAPs of BYDV-GAV; (2) the silencing of <i>STAT5B</i> led to a significant increase in BYDV-GAV retention during IAPs; and (3) the silencing of <i>C1QBP</i> resulted in a notable decrease in BYDV-GAV acquisition during the AAPs, as well as a significant increase in BYDV-GAV retention during the IAPs. These results suggest that <i>STAT5B</i> and <i>C1QBP</i> in <i>S. avenae</i> play a role in BYDV-GAV transmission. These findings highlight the functions of the <i>STAT5B</i> and <i>C1QBP</i> genes and identify <i>C1QBP</i> as a potential target gene for further RNAi-based studies to control the transmission of BYDV-GAV.https://www.mdpi.com/2073-4395/14/12/2787BYDV-GAVvector aphidacquisition accession periodsinoculation accession periods
spellingShingle Chiping Liu
Manwen Zhang
Chen Luo
Zuqing Hu
Implications of the <i>STAT5B</i> and <i>C1QBP</i> Genes of Grain Aphid <i>Sitobion avenae</i> in the Transmission of Barley Yellow Dwarf Virus
Agronomy
BYDV-GAV
vector aphid
acquisition accession periods
inoculation accession periods
title Implications of the <i>STAT5B</i> and <i>C1QBP</i> Genes of Grain Aphid <i>Sitobion avenae</i> in the Transmission of Barley Yellow Dwarf Virus
title_full Implications of the <i>STAT5B</i> and <i>C1QBP</i> Genes of Grain Aphid <i>Sitobion avenae</i> in the Transmission of Barley Yellow Dwarf Virus
title_fullStr Implications of the <i>STAT5B</i> and <i>C1QBP</i> Genes of Grain Aphid <i>Sitobion avenae</i> in the Transmission of Barley Yellow Dwarf Virus
title_full_unstemmed Implications of the <i>STAT5B</i> and <i>C1QBP</i> Genes of Grain Aphid <i>Sitobion avenae</i> in the Transmission of Barley Yellow Dwarf Virus
title_short Implications of the <i>STAT5B</i> and <i>C1QBP</i> Genes of Grain Aphid <i>Sitobion avenae</i> in the Transmission of Barley Yellow Dwarf Virus
title_sort implications of the i stat5b i and i c1qbp i genes of grain aphid i sitobion avenae i in the transmission of barley yellow dwarf virus
topic BYDV-GAV
vector aphid
acquisition accession periods
inoculation accession periods
url https://www.mdpi.com/2073-4395/14/12/2787
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AT manwenzhang implicationsoftheistat5biandic1qbpigenesofgrainaphidisitobionavenaeiinthetransmissionofbarleyyellowdwarfvirus
AT chenluo implicationsoftheistat5biandic1qbpigenesofgrainaphidisitobionavenaeiinthetransmissionofbarleyyellowdwarfvirus
AT zuqinghu implicationsoftheistat5biandic1qbpigenesofgrainaphidisitobionavenaeiinthetransmissionofbarleyyellowdwarfvirus