Amelanotic Melanoma Masquerading as a Granular Cell Lesion
Amelanotic melanoma (AM) presents a diagnostic challenge due to its wide clinical presentations, lack of pigmentation, and varied histological appearances. Immunohistochemistry plays a crucial role in the diagnosis of these lesions. Amelanotic melanoma of oral mucosa is an uncommon lesion. We report...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2013/924573 |
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| author | Deepak Pandiar Shaini Basheer P. M. Shameena S. Sudha Lakshmi J. Dhana |
| author_facet | Deepak Pandiar Shaini Basheer P. M. Shameena S. Sudha Lakshmi J. Dhana |
| author_sort | Deepak Pandiar |
| collection | DOAJ |
| description | Amelanotic melanoma (AM) presents a diagnostic challenge due to its wide clinical presentations, lack of pigmentation, and varied histological appearances. Immunohistochemistry plays a crucial role in the diagnosis of these lesions. Amelanotic melanoma of oral mucosa is an uncommon lesion. We report a case of a 50-year-old male patient with a growth on the anterior mandibular gingiva of seven-month duration. In the present case, histologically, the tumour resembled a granular cell lesion, which has not been reported previously in AM. Diagnosis was possible by a sequential panel of immunohistochemical markers, of which finally vimentin, S100, HMB45, and Melan-A were positive. The tumor was surgically excised, and postsurgical radiotherapy was given. |
| format | Article |
| id | doaj-art-084e53f27d2741998b44692387b87387 |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-084e53f27d2741998b44692387b873872025-02-03T01:06:17ZengWileyCase Reports in Dentistry2090-64472090-64552013-01-01201310.1155/2013/924573924573Amelanotic Melanoma Masquerading as a Granular Cell LesionDeepak Pandiar0Shaini Basheer1P. M. Shameena2S. Sudha3Lakshmi J. Dhana4Department of Oral and Maxillofacial Pathology, Government Dental College, Kozhikode, Kerala 673008, IndiaDepartment of Oral and Maxillofacial Pathology, Government Dental College, Kozhikode, Kerala 673008, IndiaDepartment of Oral and Maxillofacial Pathology, Government Dental College, Kozhikode, Kerala 673008, IndiaDepartment of Oral and Maxillofacial Pathology, Government Dental College, Kozhikode, Kerala 673008, IndiaDepartment of Oral and Maxillofacial Pathology, Government Dental College, Kozhikode, Kerala 673008, IndiaAmelanotic melanoma (AM) presents a diagnostic challenge due to its wide clinical presentations, lack of pigmentation, and varied histological appearances. Immunohistochemistry plays a crucial role in the diagnosis of these lesions. Amelanotic melanoma of oral mucosa is an uncommon lesion. We report a case of a 50-year-old male patient with a growth on the anterior mandibular gingiva of seven-month duration. In the present case, histologically, the tumour resembled a granular cell lesion, which has not been reported previously in AM. Diagnosis was possible by a sequential panel of immunohistochemical markers, of which finally vimentin, S100, HMB45, and Melan-A were positive. The tumor was surgically excised, and postsurgical radiotherapy was given.http://dx.doi.org/10.1155/2013/924573 |
| spellingShingle | Deepak Pandiar Shaini Basheer P. M. Shameena S. Sudha Lakshmi J. Dhana Amelanotic Melanoma Masquerading as a Granular Cell Lesion Case Reports in Dentistry |
| title | Amelanotic Melanoma Masquerading as a Granular Cell Lesion |
| title_full | Amelanotic Melanoma Masquerading as a Granular Cell Lesion |
| title_fullStr | Amelanotic Melanoma Masquerading as a Granular Cell Lesion |
| title_full_unstemmed | Amelanotic Melanoma Masquerading as a Granular Cell Lesion |
| title_short | Amelanotic Melanoma Masquerading as a Granular Cell Lesion |
| title_sort | amelanotic melanoma masquerading as a granular cell lesion |
| url | http://dx.doi.org/10.1155/2013/924573 |
| work_keys_str_mv | AT deepakpandiar amelanoticmelanomamasqueradingasagranularcelllesion AT shainibasheer amelanoticmelanomamasqueradingasagranularcelllesion AT pmshameena amelanoticmelanomamasqueradingasagranularcelllesion AT ssudha amelanoticmelanomamasqueradingasagranularcelllesion AT lakshmijdhana amelanoticmelanomamasqueradingasagranularcelllesion |