The role of fecal microbiota transplantation in type 2 diabetes mellitus treatment

In contemporary microbial research, the exploration of interactions between microorganisms and multicellular hosts constitutes a burgeoning field. The gut microbiota is increasingly acknowledged as a pivotal contributor to various disorders within the endocrine system, encompassing conditions such a...

Full description

Saved in:
Bibliographic Details
Main Authors: Huimei Wang, Shuo Li, Luping Zhang, Nan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1469165/full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832584907088461824
author Huimei Wang
Shuo Li
Luping Zhang
Nan Zhang
author_facet Huimei Wang
Shuo Li
Luping Zhang
Nan Zhang
author_sort Huimei Wang
collection DOAJ
description In contemporary microbial research, the exploration of interactions between microorganisms and multicellular hosts constitutes a burgeoning field. The gut microbiota is increasingly acknowledged as a pivotal contributor to various disorders within the endocrine system, encompassing conditions such as diabetes and thyroid diseases. A surge in research activities has been witnessed in recent years, elucidating the intricate interplay between the gut microbiota and disorders of the endocrine system. Simultaneously, fecal microbiota transplantation (FMT) has emerged as a focal point, garnering substantial attention in both biomedical and clinical spheres. Research endeavors have uncovered the remarkable therapeutic efficacy of FMT across diverse diseases, with particular emphasis on its application in addressing type 2 diabetes mellitus (T2DM) and associated com-plications. Consequently, this manuscript accentuates the intimate connection between the gut microbiota and disorders within the endocrine system, with a specific focus on exploring the potential of FMT as an intervention in the therapeutic landscape of T2DM and its complications. Furthermore, the article scrutinizes concerns inherent in treatment modalities centered around the gut microbiota, proposing viable solutions to address these issues.
format Article
id doaj-art-08498f5abbcf489bbebf12efa3e99560
institution Kabale University
issn 1664-2392
language English
publishDate 2024-12-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Endocrinology
spelling doaj-art-08498f5abbcf489bbebf12efa3e995602025-01-27T08:52:32ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922024-12-011510.3389/fendo.2024.14691651469165The role of fecal microbiota transplantation in type 2 diabetes mellitus treatmentHuimei WangShuo LiLuping ZhangNan ZhangIn contemporary microbial research, the exploration of interactions between microorganisms and multicellular hosts constitutes a burgeoning field. The gut microbiota is increasingly acknowledged as a pivotal contributor to various disorders within the endocrine system, encompassing conditions such as diabetes and thyroid diseases. A surge in research activities has been witnessed in recent years, elucidating the intricate interplay between the gut microbiota and disorders of the endocrine system. Simultaneously, fecal microbiota transplantation (FMT) has emerged as a focal point, garnering substantial attention in both biomedical and clinical spheres. Research endeavors have uncovered the remarkable therapeutic efficacy of FMT across diverse diseases, with particular emphasis on its application in addressing type 2 diabetes mellitus (T2DM) and associated com-plications. Consequently, this manuscript accentuates the intimate connection between the gut microbiota and disorders within the endocrine system, with a specific focus on exploring the potential of FMT as an intervention in the therapeutic landscape of T2DM and its complications. Furthermore, the article scrutinizes concerns inherent in treatment modalities centered around the gut microbiota, proposing viable solutions to address these issues.https://www.frontiersin.org/articles/10.3389/fendo.2024.1469165/fulltype 2 diabetes mellitusfecal microbiota transplantationgut microbiotadysbiosismetabolites
spellingShingle Huimei Wang
Shuo Li
Luping Zhang
Nan Zhang
The role of fecal microbiota transplantation in type 2 diabetes mellitus treatment
Frontiers in Endocrinology
type 2 diabetes mellitus
fecal microbiota transplantation
gut microbiota
dysbiosis
metabolites
title The role of fecal microbiota transplantation in type 2 diabetes mellitus treatment
title_full The role of fecal microbiota transplantation in type 2 diabetes mellitus treatment
title_fullStr The role of fecal microbiota transplantation in type 2 diabetes mellitus treatment
title_full_unstemmed The role of fecal microbiota transplantation in type 2 diabetes mellitus treatment
title_short The role of fecal microbiota transplantation in type 2 diabetes mellitus treatment
title_sort role of fecal microbiota transplantation in type 2 diabetes mellitus treatment
topic type 2 diabetes mellitus
fecal microbiota transplantation
gut microbiota
dysbiosis
metabolites
url https://www.frontiersin.org/articles/10.3389/fendo.2024.1469165/full
work_keys_str_mv AT huimeiwang theroleoffecalmicrobiotatransplantationintype2diabetesmellitustreatment
AT shuoli theroleoffecalmicrobiotatransplantationintype2diabetesmellitustreatment
AT lupingzhang theroleoffecalmicrobiotatransplantationintype2diabetesmellitustreatment
AT nanzhang theroleoffecalmicrobiotatransplantationintype2diabetesmellitustreatment
AT huimeiwang roleoffecalmicrobiotatransplantationintype2diabetesmellitustreatment
AT shuoli roleoffecalmicrobiotatransplantationintype2diabetesmellitustreatment
AT lupingzhang roleoffecalmicrobiotatransplantationintype2diabetesmellitustreatment
AT nanzhang roleoffecalmicrobiotatransplantationintype2diabetesmellitustreatment