The role of heparanase in pulmonary cell recruitment in response to an allergic but not non-allergic stimulus.

The role of heparanase in pulmonary cell recruitment in response to an allergic but not non-allergic stimulus.

Heparanase is an endo-β-glucuronidase that specifically cleaves heparan sulfate proteoglycans in the extracellular matrix. Expression of this enzyme is increased in several pathological conditions including inflammation. We have investigated the role of heparanase in pulmonary inflammation in the co...

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Bibliographic Details
Main Authors: Abigail Morris, Bo Wang, Ida Waern, Radhakrishnan Venkatasamy, Clive Page, Eric P Schmidt, Sara Wernersson, Jin-Ping Li, Domenico Spina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0127032
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