The Relationship Between Anthropometric Variables and Lung Function in a Severe Smoking Community Population With Ventilatory Dysfunction

ABSTRACT Background The World Health Organization estimated that 65 million individuals have chronic obstructive pulmonary disease (COPD). However, large numbers remain undiagnosed. Anthropometric variables and lung function are closely related, such as body mass index (BMI), waist circumference (WC...

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Main Authors: Tiantian Cen, Zekai Cen, Xuan Chen, Zaichun Deng, Yiming Yu, Shanshan Wang, Hongying Ma
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:The Clinical Respiratory Journal
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Online Access:https://doi.org/10.1111/crj.70076
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author Tiantian Cen
Zekai Cen
Xuan Chen
Zaichun Deng
Yiming Yu
Shanshan Wang
Hongying Ma
author_facet Tiantian Cen
Zekai Cen
Xuan Chen
Zaichun Deng
Yiming Yu
Shanshan Wang
Hongying Ma
author_sort Tiantian Cen
collection DOAJ
description ABSTRACT Background The World Health Organization estimated that 65 million individuals have chronic obstructive pulmonary disease (COPD). However, large numbers remain undiagnosed. Anthropometric variables and lung function are closely related, such as body mass index (BMI), waist circumference (WC), and waist‐to‐height ratio (WHtR). Therefore, it is essential to explore the relationship between anthropometric variables and lung function. Methods We recruited 7679 severe smokers. Severe smoking was defined as a smoking index ≥ 20 pack‐years. Among these participants, there are 6214 severe smokers with mild, moderate, and moderately severe obstructive ventilation dysfunction and 1465 severe smokers with severe and very severe obstructive ventilation dysfunction. Otherwise, participants were divided into different groups according to questionnaires and sex. Results Lung function in the severe smoking community population was associated with anthropometric variables. The study results showed that BMI was negatively associated with the risk of severe and very severe obstructive ventilation dysfunction in a severe smoking community population with ventilatory dysfunction (OR 0.791, 95% CI 0.691–0.907, p = 0.001), the COPD Population Screener (COPD‐PS) scores ≥ 5 group (OR 0.787, 95% CI 0.688–0.902, p = 0.001), the COPD Screening Questionnaire (COPD‐SQ) scores ≥ 16 group (OR 0.791, 95% CI 0.689–0.908, p = 0.001), the COPD‐PS scores ≥ 5 and COPD‐SQ scores ≥ 16 group (OR 0.730, 95% CI 0.603–0.884, p = 0.001) and the male group (OR 0.813, 95% CI 0.708–0.933, p = 0.003). The study showed that WC was also associated with obstructive ventilation dysfunction. Conclusion Low BMI and WC were independent risk factors for severe and very severe obstructive ventilation dysfunction in the severe smoking community Chinese population with ventilatory dysfunction. Collecting COPD questionnaires may help manage lung function in the community population.
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spelling doaj-art-082f04ec77c7416eabb7d330ff4d11fe2025-08-20T03:21:39ZengWileyThe Clinical Respiratory Journal1752-69811752-699X2025-05-01195n/an/a10.1111/crj.70076The Relationship Between Anthropometric Variables and Lung Function in a Severe Smoking Community Population With Ventilatory DysfunctionTiantian Cen0Zekai Cen1Xuan Chen2Zaichun Deng3Yiming Yu4Shanshan Wang5Hongying Ma6Department of Respiratory and Critical Care Medicine, Key Laboratory of Respiratory Disease of Ningbo The First Affiliated Hospital of Ningbo University Ningbo Zhejiang ChinaDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Respiratory Disease of Ningbo The First Affiliated Hospital of Ningbo University Ningbo Zhejiang ChinaDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Respiratory Disease of Ningbo The First Affiliated Hospital of Ningbo University Ningbo Zhejiang ChinaDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Respiratory Disease of Ningbo The First Affiliated Hospital of Ningbo University Ningbo Zhejiang ChinaDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Respiratory Disease of Ningbo The First Affiliated Hospital of Ningbo University Ningbo Zhejiang ChinaDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Respiratory Disease of Ningbo The First Affiliated Hospital of Ningbo University Ningbo Zhejiang ChinaDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Respiratory Disease of Ningbo The First Affiliated Hospital of Ningbo University Ningbo Zhejiang ChinaABSTRACT Background The World Health Organization estimated that 65 million individuals have chronic obstructive pulmonary disease (COPD). However, large numbers remain undiagnosed. Anthropometric variables and lung function are closely related, such as body mass index (BMI), waist circumference (WC), and waist‐to‐height ratio (WHtR). Therefore, it is essential to explore the relationship between anthropometric variables and lung function. Methods We recruited 7679 severe smokers. Severe smoking was defined as a smoking index ≥ 20 pack‐years. Among these participants, there are 6214 severe smokers with mild, moderate, and moderately severe obstructive ventilation dysfunction and 1465 severe smokers with severe and very severe obstructive ventilation dysfunction. Otherwise, participants were divided into different groups according to questionnaires and sex. Results Lung function in the severe smoking community population was associated with anthropometric variables. The study results showed that BMI was negatively associated with the risk of severe and very severe obstructive ventilation dysfunction in a severe smoking community population with ventilatory dysfunction (OR 0.791, 95% CI 0.691–0.907, p = 0.001), the COPD Population Screener (COPD‐PS) scores ≥ 5 group (OR 0.787, 95% CI 0.688–0.902, p = 0.001), the COPD Screening Questionnaire (COPD‐SQ) scores ≥ 16 group (OR 0.791, 95% CI 0.689–0.908, p = 0.001), the COPD‐PS scores ≥ 5 and COPD‐SQ scores ≥ 16 group (OR 0.730, 95% CI 0.603–0.884, p = 0.001) and the male group (OR 0.813, 95% CI 0.708–0.933, p = 0.003). The study showed that WC was also associated with obstructive ventilation dysfunction. Conclusion Low BMI and WC were independent risk factors for severe and very severe obstructive ventilation dysfunction in the severe smoking community Chinese population with ventilatory dysfunction. Collecting COPD questionnaires may help manage lung function in the community population.https://doi.org/10.1111/crj.70076body mass indexchronic obstructive pulmonary diseasechronic obstructive pulmonary disease population screenerchronic obstructive pulmonary disease screening questionnairelung functionwaist circumference
spellingShingle Tiantian Cen
Zekai Cen
Xuan Chen
Zaichun Deng
Yiming Yu
Shanshan Wang
Hongying Ma
The Relationship Between Anthropometric Variables and Lung Function in a Severe Smoking Community Population With Ventilatory Dysfunction
The Clinical Respiratory Journal
body mass index
chronic obstructive pulmonary disease
chronic obstructive pulmonary disease population screener
chronic obstructive pulmonary disease screening questionnaire
lung function
waist circumference
title The Relationship Between Anthropometric Variables and Lung Function in a Severe Smoking Community Population With Ventilatory Dysfunction
title_full The Relationship Between Anthropometric Variables and Lung Function in a Severe Smoking Community Population With Ventilatory Dysfunction
title_fullStr The Relationship Between Anthropometric Variables and Lung Function in a Severe Smoking Community Population With Ventilatory Dysfunction
title_full_unstemmed The Relationship Between Anthropometric Variables and Lung Function in a Severe Smoking Community Population With Ventilatory Dysfunction
title_short The Relationship Between Anthropometric Variables and Lung Function in a Severe Smoking Community Population With Ventilatory Dysfunction
title_sort relationship between anthropometric variables and lung function in a severe smoking community population with ventilatory dysfunction
topic body mass index
chronic obstructive pulmonary disease
chronic obstructive pulmonary disease population screener
chronic obstructive pulmonary disease screening questionnaire
lung function
waist circumference
url https://doi.org/10.1111/crj.70076
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