Interchangeability of glibenclamide-containing drugs
The article analyses the problem of interchangeability of glibenclamide-containing drugs that sometimes lack therapeutic equivalence even though their bioequivalence has been proven. The authors formulated the key factors affecting interchangeability of glibenclamide drugs and highlighted conditions...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’)
2018-02-01
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| Series: | Регуляторные исследования и экспертиза лекарственных средств |
| Subjects: | |
| Online Access: | https://www.vedomostincesmp.ru/jour/article/view/142 |
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| _version_ | 1849249592176017408 |
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| author | G. I. Gorodetskaya E. V. Shikh M. V. Zhuravleva S. Yu. Serebrova E. A. Sokova O. V. Muslimova T. V. Aleksandrova I. A. Mazerkina S. G. Rudnev |
| author_facet | G. I. Gorodetskaya E. V. Shikh M. V. Zhuravleva S. Yu. Serebrova E. A. Sokova O. V. Muslimova T. V. Aleksandrova I. A. Mazerkina S. G. Rudnev |
| author_sort | G. I. Gorodetskaya |
| collection | DOAJ |
| description | The article analyses the problem of interchangeability of glibenclamide-containing drugs that sometimes lack therapeutic equivalence even though their bioequivalence has been proven. The authors formulated the key factors affecting interchangeability of glibenclamide drugs and highlighted conditions that compromise interchangeability. Special attention was given to clinical pharmacology of glibenclamide and adverse reactions associated with sulfonylurea products. The article offers a summary of the main groups of glibenclamide drugs. It also substantiates the need for better coordination of production and clinical use of glibenclamide drugs which will help to ensure the comparability of generic and reference glibenclamide drugs in the long run. |
| format | Article |
| id | doaj-art-082eb3276cc3467e82a04a4ed916e3ea |
| institution | Kabale University |
| issn | 3034-3062 3034-3453 |
| language | Russian |
| publishDate | 2018-02-01 |
| publisher | Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) |
| record_format | Article |
| series | Регуляторные исследования и экспертиза лекарственных средств |
| spelling | doaj-art-082eb3276cc3467e82a04a4ed916e3ea2025-08-20T03:57:31ZrusFederal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’)Регуляторные исследования и экспертиза лекарственных средств3034-30623034-34532018-02-0174199211140Interchangeability of glibenclamide-containing drugsG. I. Gorodetskaya0E. V. Shikh1M. V. Zhuravleva2S. Yu. Serebrova3E. A. Sokova4O. V. Muslimova5T. V. Aleksandrova6I. A. Mazerkina7S. G. Rudnev8Scientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsThe article analyses the problem of interchangeability of glibenclamide-containing drugs that sometimes lack therapeutic equivalence even though their bioequivalence has been proven. The authors formulated the key factors affecting interchangeability of glibenclamide drugs and highlighted conditions that compromise interchangeability. Special attention was given to clinical pharmacology of glibenclamide and adverse reactions associated with sulfonylurea products. The article offers a summary of the main groups of glibenclamide drugs. It also substantiates the need for better coordination of production and clinical use of glibenclamide drugs which will help to ensure the comparability of generic and reference glibenclamide drugs in the long run.https://www.vedomostincesmp.ru/jour/article/view/142взаимозаменяемостьбиоэквивалентностьтерапевтическая эквивалентностьвоспроизведенные препаратыпрепараты глибенкламидаinterchangeabilitybioequivalencetherapeutic equivalencegeneric drugsglibenclamide drugs |
| spellingShingle | G. I. Gorodetskaya E. V. Shikh M. V. Zhuravleva S. Yu. Serebrova E. A. Sokova O. V. Muslimova T. V. Aleksandrova I. A. Mazerkina S. G. Rudnev Interchangeability of glibenclamide-containing drugs Регуляторные исследования и экспертиза лекарственных средств взаимозаменяемость биоэквивалентность терапевтическая эквивалентность воспроизведенные препараты препараты глибенкламида interchangeability bioequivalence therapeutic equivalence generic drugs glibenclamide drugs |
| title | Interchangeability of glibenclamide-containing drugs |
| title_full | Interchangeability of glibenclamide-containing drugs |
| title_fullStr | Interchangeability of glibenclamide-containing drugs |
| title_full_unstemmed | Interchangeability of glibenclamide-containing drugs |
| title_short | Interchangeability of glibenclamide-containing drugs |
| title_sort | interchangeability of glibenclamide containing drugs |
| topic | взаимозаменяемость биоэквивалентность терапевтическая эквивалентность воспроизведенные препараты препараты глибенкламида interchangeability bioequivalence therapeutic equivalence generic drugs glibenclamide drugs |
| url | https://www.vedomostincesmp.ru/jour/article/view/142 |
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