Modern trends in identification of causative agents in infective endocarditis
Advances in the diagnosis and treatment of patients with infectious endocarditis are limited by the high frequency of cases with an unknown etiology and imperfection of microbiological (cultural) methods. To overcome these problems new approaches to the identification of infectious endocarditis path...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2021-03-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | https://www.rpcardio.online/jour/article/view/2401 |
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| author | E. O. Kotova E. A. Domonova Zh. D. Kobalava J. L. Karaulova A. S. Pisaryuk A. V. Balatskiy V. G. Akimkin |
| author_facet | E. O. Kotova E. A. Domonova Zh. D. Kobalava J. L. Karaulova A. S. Pisaryuk A. V. Balatskiy V. G. Akimkin |
| author_sort | E. O. Kotova |
| collection | DOAJ |
| description | Advances in the diagnosis and treatment of patients with infectious endocarditis are limited by the high frequency of cases with an unknown etiology and imperfection of microbiological (cultural) methods. To overcome these problems new approaches to the identification of infectious endocarditis pathogens were introduced, which allowed achieving certain positive results. However, it should be noted that despite the wide variety of diagnostic tools currently used, there is no ideal method for etiological laboratory diagnosis of infectious endocarditis. The article discusses the features and place of immunochemical, molecular biological (MALDI-TOF MS, real-time PCR, sequencing, in situ fluorescence hybridization, metagenomic methods, etc.), immunohistochemical methods, and their advantages and limitations. |
| format | Article |
| id | doaj-art-082c72c82efd4028ba06ead2ac464057 |
| institution | Kabale University |
| issn | 1819-6446 2225-3653 |
| language | English |
| publishDate | 2021-03-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj-art-082c72c82efd4028ba06ead2ac4640572025-08-23T10:00:33ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532021-03-0117115316410.20996/1819-6446-2021-02-141853Modern trends in identification of causative agents in infective endocarditisE. O. Kotova0E. A. Domonova1Zh. D. Kobalava2J. L. Karaulova3A. S. Pisaryuk4A. V. Balatskiy5V. G. Akimkin6Peoples’ Friendship University of Russia (RUDN)Central Research Institute of EpidemiologyPeoples’ Friendship University of Russia (RUDN)Peoples’ Friendship University of Russia (RUDN)Peoples’ Friendship University of Russia (RUDN); Moscow City Hospital named after V.V. VinogradovLomonosov Moscow State UniversityCentral Research Institute of EpidemiologyAdvances in the diagnosis and treatment of patients with infectious endocarditis are limited by the high frequency of cases with an unknown etiology and imperfection of microbiological (cultural) methods. To overcome these problems new approaches to the identification of infectious endocarditis pathogens were introduced, which allowed achieving certain positive results. However, it should be noted that despite the wide variety of diagnostic tools currently used, there is no ideal method for etiological laboratory diagnosis of infectious endocarditis. The article discusses the features and place of immunochemical, molecular biological (MALDI-TOF MS, real-time PCR, sequencing, in situ fluorescence hybridization, metagenomic methods, etc.), immunohistochemical methods, and their advantages and limitations.https://www.rpcardio.online/jour/article/view/2401culture negative infective endocarditismicrobiological methodsmaldi-tof msreal-time pcrmicrobiologistic |
| spellingShingle | E. O. Kotova E. A. Domonova Zh. D. Kobalava J. L. Karaulova A. S. Pisaryuk A. V. Balatskiy V. G. Akimkin Modern trends in identification of causative agents in infective endocarditis Рациональная фармакотерапия в кардиологии culture negative infective endocarditis microbiological methods maldi-tof ms real-time pcr microbiologistic |
| title | Modern trends in identification of causative agents in infective endocarditis |
| title_full | Modern trends in identification of causative agents in infective endocarditis |
| title_fullStr | Modern trends in identification of causative agents in infective endocarditis |
| title_full_unstemmed | Modern trends in identification of causative agents in infective endocarditis |
| title_short | Modern trends in identification of causative agents in infective endocarditis |
| title_sort | modern trends in identification of causative agents in infective endocarditis |
| topic | culture negative infective endocarditis microbiological methods maldi-tof ms real-time pcr microbiologistic |
| url | https://www.rpcardio.online/jour/article/view/2401 |
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