A Case of Posttransfusion Purpura with Severe Refractory Thrombocytopenia but No Cutaneous Manifestations
Posttransfusion purpura is a serious adverse effect of transfusion due to HPA-antibodies. A young female was diagnosed with acute leukaemia, and treatment commenced. Severe thrombocytopenia ensued. No platelet increment was achieved despite transfusions with buffy coat, HLA-compatible, and HPA-1a ne...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2018/8187659 |
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| author | Jagjit Singh Bhamra Per Ole Iversen Thomas Kjenner Titze Geir Erland Tjønnfjord Çiğdem Akalın Akkök |
| author_facet | Jagjit Singh Bhamra Per Ole Iversen Thomas Kjenner Titze Geir Erland Tjønnfjord Çiğdem Akalın Akkök |
| author_sort | Jagjit Singh Bhamra |
| collection | DOAJ |
| description | Posttransfusion purpura is a serious adverse effect of transfusion due to HPA-antibodies. A young female was diagnosed with acute leukaemia, and treatment commenced. Severe thrombocytopenia ensued. No platelet increment was achieved despite transfusions with buffy coat, HLA-compatible, and HPA-1a negative platelets. The workup indicated the presence of anti-HPA-1a. When the diagnosis of posttransfusion purpura was sufficiently substantiated, she had experienced a fatal intracerebral haemorrhage. |
| format | Article |
| id | doaj-art-08290d78b91a45afbd93d5f75136537f |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-08290d78b91a45afbd93d5f75136537f2025-08-20T03:55:32ZengWileyCase Reports in Hematology2090-65602090-65792018-01-01201810.1155/2018/81876598187659A Case of Posttransfusion Purpura with Severe Refractory Thrombocytopenia but No Cutaneous ManifestationsJagjit Singh Bhamra0Per Ole Iversen1Thomas Kjenner Titze2Geir Erland Tjønnfjord3Çiğdem Akalın Akkök4Department of Immunology and Transfusion Medicine, Oslo University Hospital, Oslo, NorwayDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, NorwayDepartment of Immunology and Transfusion Medicine, Oslo University Hospital, Oslo, NorwayDepartment of Haematology, Oslo University Hospital, Oslo, NorwayDepartment of Immunology and Transfusion Medicine, Oslo University Hospital, Oslo, NorwayPosttransfusion purpura is a serious adverse effect of transfusion due to HPA-antibodies. A young female was diagnosed with acute leukaemia, and treatment commenced. Severe thrombocytopenia ensued. No platelet increment was achieved despite transfusions with buffy coat, HLA-compatible, and HPA-1a negative platelets. The workup indicated the presence of anti-HPA-1a. When the diagnosis of posttransfusion purpura was sufficiently substantiated, she had experienced a fatal intracerebral haemorrhage.http://dx.doi.org/10.1155/2018/8187659 |
| spellingShingle | Jagjit Singh Bhamra Per Ole Iversen Thomas Kjenner Titze Geir Erland Tjønnfjord Çiğdem Akalın Akkök A Case of Posttransfusion Purpura with Severe Refractory Thrombocytopenia but No Cutaneous Manifestations Case Reports in Hematology |
| title | A Case of Posttransfusion Purpura with Severe Refractory Thrombocytopenia but No Cutaneous Manifestations |
| title_full | A Case of Posttransfusion Purpura with Severe Refractory Thrombocytopenia but No Cutaneous Manifestations |
| title_fullStr | A Case of Posttransfusion Purpura with Severe Refractory Thrombocytopenia but No Cutaneous Manifestations |
| title_full_unstemmed | A Case of Posttransfusion Purpura with Severe Refractory Thrombocytopenia but No Cutaneous Manifestations |
| title_short | A Case of Posttransfusion Purpura with Severe Refractory Thrombocytopenia but No Cutaneous Manifestations |
| title_sort | case of posttransfusion purpura with severe refractory thrombocytopenia but no cutaneous manifestations |
| url | http://dx.doi.org/10.1155/2018/8187659 |
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