A study of endocrine profile in premenopausal women with hirsutism
Background The aim of the study was to find the endocrinal profile of patients with hirsutism presenting to dermatology OPD. Hirsutism is defined objectively by Modified Ferriman-Gallwey score ≥ 8 (mFG). Methods The study included 44 premenopausal women in whom after history and clinical examination...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer – Medknow Publications
2014-07-01
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| Series: | Journal of Integrated Health Sciences |
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| Online Access: | https://journals.lww.com/10.4103/2347-6486.239542 |
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| author | J Lakhani Som J Lakhani Om R C Raval |
| author_facet | J Lakhani Som J Lakhani Om R C Raval |
| author_sort | J Lakhani Som |
| collection | DOAJ |
| description | Background
The aim of the study was to find the endocrinal profile of patients with hirsutism presenting to dermatology OPD. Hirsutism is defined objectively by Modified Ferriman-Gallwey score ≥ 8 (mFG).
Methods
The study included 44 premenopausal women in whom after history and clinical examination, endocrine tests were done which included Diabetes profile, TSH, FSH, LH, Free and Total Testosterone, DHEAS, Fasting insulin,17-hydroxyprogesterone and Prolactin.
Results
Mean age of the patients was 20-29 years while duration of symptoms was of 3 years. Upper lip was the most common site for hair growth while upper arm was the least common. Hair loss and menstrual irregularity were common associated findings. Obesity had a significant correlation with severity of hirsutism. Mean total testosterone in study patients was 64.31 ng/dl. There was no correlation between severity of hirsutism and any of the endocrinal tests. Idiopathic hirsutism (IH) was the most common diagnosis, closely followed by PCOS. We detected 1 case of Non classical Congenital Adrenal Hyperplasia and no cases of Ovarian or Adrenal tumors. Serum testosterone and LH/FSH ratio were significantly elevated in PCOS group as compared to IH group.
Conclusion
Obesity had a strong relation with severity of Hirsutism independent of other parameters. Fasting blood sugar, serum testosterone, TSH and Fasting insulin levels had no correlation with severity of Hirsutism. |
| format | Article |
| id | doaj-art-08255a5fa7e348aeb9ddbf2b72be3662 |
| institution | OA Journals |
| issn | 2347-6486 2347-6494 |
| language | English |
| publishDate | 2014-07-01 |
| publisher | Wolters Kluwer – Medknow Publications |
| record_format | Article |
| series | Journal of Integrated Health Sciences |
| spelling | doaj-art-08255a5fa7e348aeb9ddbf2b72be36622025-08-20T02:15:54ZengWolters Kluwer – Medknow PublicationsJournal of Integrated Health Sciences2347-64862347-64942014-07-0122172210.4103/2347-6486.239542A study of endocrine profile in premenopausal women with hirsutismJ Lakhani SomJ Lakhani OmR C RavalBackground The aim of the study was to find the endocrinal profile of patients with hirsutism presenting to dermatology OPD. Hirsutism is defined objectively by Modified Ferriman-Gallwey score ≥ 8 (mFG). Methods The study included 44 premenopausal women in whom after history and clinical examination, endocrine tests were done which included Diabetes profile, TSH, FSH, LH, Free and Total Testosterone, DHEAS, Fasting insulin,17-hydroxyprogesterone and Prolactin. Results Mean age of the patients was 20-29 years while duration of symptoms was of 3 years. Upper lip was the most common site for hair growth while upper arm was the least common. Hair loss and menstrual irregularity were common associated findings. Obesity had a significant correlation with severity of hirsutism. Mean total testosterone in study patients was 64.31 ng/dl. There was no correlation between severity of hirsutism and any of the endocrinal tests. Idiopathic hirsutism (IH) was the most common diagnosis, closely followed by PCOS. We detected 1 case of Non classical Congenital Adrenal Hyperplasia and no cases of Ovarian or Adrenal tumors. Serum testosterone and LH/FSH ratio were significantly elevated in PCOS group as compared to IH group. Conclusion Obesity had a strong relation with severity of Hirsutism independent of other parameters. Fasting blood sugar, serum testosterone, TSH and Fasting insulin levels had no correlation with severity of Hirsutism.https://journals.lww.com/10.4103/2347-6486.239542hirsutismmodified ferriman-gallwey score (mfg). |
| spellingShingle | J Lakhani Som J Lakhani Om R C Raval A study of endocrine profile in premenopausal women with hirsutism Journal of Integrated Health Sciences hirsutism modified ferriman-gallwey score (mfg). |
| title | A study of endocrine profile in premenopausal women with hirsutism |
| title_full | A study of endocrine profile in premenopausal women with hirsutism |
| title_fullStr | A study of endocrine profile in premenopausal women with hirsutism |
| title_full_unstemmed | A study of endocrine profile in premenopausal women with hirsutism |
| title_short | A study of endocrine profile in premenopausal women with hirsutism |
| title_sort | study of endocrine profile in premenopausal women with hirsutism |
| topic | hirsutism modified ferriman-gallwey score (mfg). |
| url | https://journals.lww.com/10.4103/2347-6486.239542 |
| work_keys_str_mv | AT jlakhanisom astudyofendocrineprofileinpremenopausalwomenwithhirsutism AT jlakhaniom astudyofendocrineprofileinpremenopausalwomenwithhirsutism AT rcraval astudyofendocrineprofileinpremenopausalwomenwithhirsutism AT jlakhanisom studyofendocrineprofileinpremenopausalwomenwithhirsutism AT jlakhaniom studyofendocrineprofileinpremenopausalwomenwithhirsutism AT rcraval studyofendocrineprofileinpremenopausalwomenwithhirsutism |