Construct Validity and Internal Consistency of the Italian Version of the PedsQL<sup>TM</sup> 4.0 Generic Core Scale and PedsQL<sup>TM</sup> 3.0 Cerebral Palsy Module
Background: Health-related quality of life (HRQoL) has emerged as a meaningful outcome measure in clinical trials and healthcare interventions in children with cerebral palsy (CwCP). We assessed the construct validity and internal consistency of the Italian version of the Paediatric QoL inventory (P...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-06-01
|
| Series: | Children |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9067/12/6/749 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849432181346140160 |
|---|---|
| author | Ilaria Pedrinelli Sofia Biagi Domenico Marco Romeo Elisa Musto Valeria Fagiani Martina Lanza Erika Guastafierro Alice Colombo Andrea Giordano Cristina Montomoli Cristiana Rezzani Tiziana Casalino Eugenio Mercuri Daria Riva Matilde Leonardi Giovanni Baranello Emanuela Pagliano |
| author_facet | Ilaria Pedrinelli Sofia Biagi Domenico Marco Romeo Elisa Musto Valeria Fagiani Martina Lanza Erika Guastafierro Alice Colombo Andrea Giordano Cristina Montomoli Cristiana Rezzani Tiziana Casalino Eugenio Mercuri Daria Riva Matilde Leonardi Giovanni Baranello Emanuela Pagliano |
| author_sort | Ilaria Pedrinelli |
| collection | DOAJ |
| description | Background: Health-related quality of life (HRQoL) has emerged as a meaningful outcome measure in clinical trials and healthcare interventions in children with cerebral palsy (CwCP). We assessed the construct validity and internal consistency of the Italian version of the Paediatric QoL inventory (PedsQL<sup>TM</sup>) 4.0 Generic Core Scales (GCS) and PedsQL<sup>TM</sup> 3.0 Cerebral Palsy Module (CPM). Methods: A total of 125 CwCP and their parents were enrolled. Participants completed both the GCS and the CPM modules, and the results were compared to those of a sample of 121 healthy peers and their parents. The dimensionality of the two modules was assessed through exploratory factor analysis. Construct validity was assessed by a known-groups method evaluating the differences between CwCP and healthy sample. Results: Only a few GCS subscales were unidimensional, while all CPM subscales proved to be unidimensional, except for the Speech and Communication subscales of child self-reports. GCS internal consistency was good for all subscales of the parent proxy-reports, as well as for the Physical Activities and Psychosocial Health subscales of child self-reports. CPM internal consistency was good for both parent proxy-reports and—with a few exceptions—child self-reports. As for the PedsQL<sup>TM</sup> validity, the GCS proved effective in discriminating between CwCP and healthy participants; the CPM showed a significant association between lower neurofunctional abilities and lower HRQoL. Parent–child concordance shows that child self-report scores were always higher than the those of the proxy-reports for both the GCS and CPM modules. Conclusions: The present study confirms the internal consistency and construct validity of the Italian version of both PedsQL<sup>TM</sup> modules. In CwCP, greater functional disability resulted in lower HRQoL scores, and there was significant discrepancy between the parent and child ratings. |
| format | Article |
| id | doaj-art-0824bb643ef44f73ba1d74f7c8e7a099 |
| institution | Kabale University |
| issn | 2227-9067 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj-art-0824bb643ef44f73ba1d74f7c8e7a0992025-08-20T03:27:26ZengMDPI AGChildren2227-90672025-06-0112674910.3390/children12060749Construct Validity and Internal Consistency of the Italian Version of the PedsQL<sup>TM</sup> 4.0 Generic Core Scale and PedsQL<sup>TM</sup> 3.0 Cerebral Palsy ModuleIlaria Pedrinelli0Sofia Biagi1Domenico Marco Romeo2Elisa Musto3Valeria Fagiani4Martina Lanza5Erika Guastafierro6Alice Colombo7Andrea Giordano8Cristina Montomoli9Cristiana Rezzani10Tiziana Casalino11Eugenio Mercuri12Daria Riva13Matilde Leonardi14Giovanni Baranello15Emanuela Pagliano16Pediatric Neuroscience Department, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyPediatric Neuroscience Department, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyPaediatric Neurology Unit, Catholic University, 00168 Rome, ItalyPaediatric Neurology Unit, Catholic University, 00168 Rome, ItalyEmergency Department, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico Milan, 20122 Milan, ItalyNeurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyNeurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyNeurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyNeurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyDepartment of Public Health Neuroscience, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, ItalyDepartment of Public Health Neuroscience, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, ItalyPediatric Neuroscience Department, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyPaediatric Neurology Unit, Catholic University, 00168 Rome, ItalyPediatric Neuroscience Department, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyNeurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyPaediatric Neurology/Neuromuscular Disorders, University College London, Great Ormond Street Institute of Child Health, Great Ormond Street Hospital NHS Foundation Trust, London WC1N 1EH, UKPediatric Neuroscience Department, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyBackground: Health-related quality of life (HRQoL) has emerged as a meaningful outcome measure in clinical trials and healthcare interventions in children with cerebral palsy (CwCP). We assessed the construct validity and internal consistency of the Italian version of the Paediatric QoL inventory (PedsQL<sup>TM</sup>) 4.0 Generic Core Scales (GCS) and PedsQL<sup>TM</sup> 3.0 Cerebral Palsy Module (CPM). Methods: A total of 125 CwCP and their parents were enrolled. Participants completed both the GCS and the CPM modules, and the results were compared to those of a sample of 121 healthy peers and their parents. The dimensionality of the two modules was assessed through exploratory factor analysis. Construct validity was assessed by a known-groups method evaluating the differences between CwCP and healthy sample. Results: Only a few GCS subscales were unidimensional, while all CPM subscales proved to be unidimensional, except for the Speech and Communication subscales of child self-reports. GCS internal consistency was good for all subscales of the parent proxy-reports, as well as for the Physical Activities and Psychosocial Health subscales of child self-reports. CPM internal consistency was good for both parent proxy-reports and—with a few exceptions—child self-reports. As for the PedsQL<sup>TM</sup> validity, the GCS proved effective in discriminating between CwCP and healthy participants; the CPM showed a significant association between lower neurofunctional abilities and lower HRQoL. Parent–child concordance shows that child self-report scores were always higher than the those of the proxy-reports for both the GCS and CPM modules. Conclusions: The present study confirms the internal consistency and construct validity of the Italian version of both PedsQL<sup>TM</sup> modules. In CwCP, greater functional disability resulted in lower HRQoL scores, and there was significant discrepancy between the parent and child ratings.https://www.mdpi.com/2227-9067/12/6/749Cerebral Palsychildrenhealth-related quality of lifeItalian populationPedsQL |
| spellingShingle | Ilaria Pedrinelli Sofia Biagi Domenico Marco Romeo Elisa Musto Valeria Fagiani Martina Lanza Erika Guastafierro Alice Colombo Andrea Giordano Cristina Montomoli Cristiana Rezzani Tiziana Casalino Eugenio Mercuri Daria Riva Matilde Leonardi Giovanni Baranello Emanuela Pagliano Construct Validity and Internal Consistency of the Italian Version of the PedsQL<sup>TM</sup> 4.0 Generic Core Scale and PedsQL<sup>TM</sup> 3.0 Cerebral Palsy Module Children Cerebral Palsy children health-related quality of life Italian population PedsQL |
| title | Construct Validity and Internal Consistency of the Italian Version of the PedsQL<sup>TM</sup> 4.0 Generic Core Scale and PedsQL<sup>TM</sup> 3.0 Cerebral Palsy Module |
| title_full | Construct Validity and Internal Consistency of the Italian Version of the PedsQL<sup>TM</sup> 4.0 Generic Core Scale and PedsQL<sup>TM</sup> 3.0 Cerebral Palsy Module |
| title_fullStr | Construct Validity and Internal Consistency of the Italian Version of the PedsQL<sup>TM</sup> 4.0 Generic Core Scale and PedsQL<sup>TM</sup> 3.0 Cerebral Palsy Module |
| title_full_unstemmed | Construct Validity and Internal Consistency of the Italian Version of the PedsQL<sup>TM</sup> 4.0 Generic Core Scale and PedsQL<sup>TM</sup> 3.0 Cerebral Palsy Module |
| title_short | Construct Validity and Internal Consistency of the Italian Version of the PedsQL<sup>TM</sup> 4.0 Generic Core Scale and PedsQL<sup>TM</sup> 3.0 Cerebral Palsy Module |
| title_sort | construct validity and internal consistency of the italian version of the pedsql sup tm sup 4 0 generic core scale and pedsql sup tm sup 3 0 cerebral palsy module |
| topic | Cerebral Palsy children health-related quality of life Italian population PedsQL |
| url | https://www.mdpi.com/2227-9067/12/6/749 |
| work_keys_str_mv | AT ilariapedrinelli constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT sofiabiagi constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT domenicomarcoromeo constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT elisamusto constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT valeriafagiani constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT martinalanza constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT erikaguastafierro constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT alicecolombo constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT andreagiordano constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT cristinamontomoli constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT cristianarezzani constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT tizianacasalino constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT eugeniomercuri constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT dariariva constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT matildeleonardi constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT giovannibaranello constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule AT emanuelapagliano constructvalidityandinternalconsistencyoftheitalianversionofthepedsqlsuptmsup40genericcorescaleandpedsqlsuptmsup30cerebralpalsymodule |