Research Status and Prospect of Amphibian Symbiotic Microbiota

Amphibians are the most severely threatened vertebrate group in terms of biodiversity. The microbiota that coexist in a mutualistic relationship with amphibians play a crucial role in shaping their health status, reproductive efficiency, and environmental adaptability. Understanding the relationship...

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Main Authors: Ziyi Wang, Yuting Wang, Zhirong He, Siyu Wu, Suyue Wang, Na Zhao, Wei Zhu, Jianping Jiang, Supen Wang
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Animals
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Online Access:https://www.mdpi.com/2076-2615/15/7/934
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author Ziyi Wang
Yuting Wang
Zhirong He
Siyu Wu
Suyue Wang
Na Zhao
Wei Zhu
Jianping Jiang
Supen Wang
author_facet Ziyi Wang
Yuting Wang
Zhirong He
Siyu Wu
Suyue Wang
Na Zhao
Wei Zhu
Jianping Jiang
Supen Wang
author_sort Ziyi Wang
collection DOAJ
description Amphibians are the most severely threatened vertebrate group in terms of biodiversity. The microbiota that coexist in a mutualistic relationship with amphibians play a crucial role in shaping their health status, reproductive efficiency, and environmental adaptability. Understanding the relationship between amphibians and microbiota is vital for elucidating the causes of amphibian diseases and developing effective prevention and control techniques, which in turn is significant for enhancing the effectiveness of amphibian diversity conservation. The main findings of this article are as follows: Firstly, it provides an overview of the systematic assessment and analysis methods regarding the importance of amphibians and their symbiotic microbiota, detailing the primary research techniques currently employed. Secondly, it discusses the impacts of environmental and biological factors on the characteristics of amphibian symbiotic microbial communities, including dimensions such as altitude, temperature fluctuations, and host dietary habits. Finally, the future directions of research on amphibian symbiotic microbiota are examined, with five recommendations presented: (1) Establish a comprehensive sample library and database of amphibians and their symbiotic microbiota to create a solid foundation for scientific research. (2) Explore the coevolutionary paths between amphibians and symbiotic microbiota to clarify the dynamic evolutionary patterns and principles of their interactions. (3) Strengthen research on specific areas of amphibians, especially the microbial communities in the oral cavity and cloaca. (4) Enhance research on the symbiotic microbiota of the Gymnophiona. (5) Strengthen international cooperation to build cross-border research platforms and jointly promote the rapid development of global amphibian symbiotic microbiology. This article summarizes the current research progress on the interaction between amphibians and their symbiotic microbiota (not necessarily mutualistic). It discusses the conservation of amphibian biodiversity from the perspective of their symbiotic microbial communities and provides a forward-looking analysis of future research directions. It aims to provide rich background information for understanding the complexity of this symbiotic system, while also having significant value in enhancing the effectiveness of amphibian biodiversity conservation.
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spelling doaj-art-08202f4f6b0846ec99d697aad49a96a42025-08-20T03:06:32ZengMDPI AGAnimals2076-26152025-03-0115793410.3390/ani15070934Research Status and Prospect of Amphibian Symbiotic MicrobiotaZiyi Wang0Yuting Wang1Zhirong He2Siyu Wu3Suyue Wang4Na Zhao5Wei Zhu6Jianping Jiang7Supen Wang8The Anhui Provincial Key Laboratory of Biodiversity Conservation and Ecological Security in the Yangtze River Basin, College of Life Sciences, Anhui Normal University, Wuhu 241000, ChinaThe Anhui Provincial Key Laboratory of Biodiversity Conservation and Ecological Security in the Yangtze River Basin, College of Life Sciences, Anhui Normal University, Wuhu 241000, ChinaThe Anhui Provincial Key Laboratory of Biodiversity Conservation and Ecological Security in the Yangtze River Basin, College of Life Sciences, Anhui Normal University, Wuhu 241000, ChinaThe Anhui Provincial Key Laboratory of Biodiversity Conservation and Ecological Security in the Yangtze River Basin, College of Life Sciences, Anhui Normal University, Wuhu 241000, ChinaThe Anhui Provincial Key Laboratory of Biodiversity Conservation and Ecological Security in the Yangtze River Basin, College of Life Sciences, Anhui Normal University, Wuhu 241000, ChinaThe Anhui Provincial Key Laboratory of Biodiversity Conservation and Ecological Security in the Yangtze River Basin, College of Life Sciences, Anhui Normal University, Wuhu 241000, ChinaChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, ChinaChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, ChinaThe Anhui Provincial Key Laboratory of Biodiversity Conservation and Ecological Security in the Yangtze River Basin, College of Life Sciences, Anhui Normal University, Wuhu 241000, ChinaAmphibians are the most severely threatened vertebrate group in terms of biodiversity. The microbiota that coexist in a mutualistic relationship with amphibians play a crucial role in shaping their health status, reproductive efficiency, and environmental adaptability. Understanding the relationship between amphibians and microbiota is vital for elucidating the causes of amphibian diseases and developing effective prevention and control techniques, which in turn is significant for enhancing the effectiveness of amphibian diversity conservation. The main findings of this article are as follows: Firstly, it provides an overview of the systematic assessment and analysis methods regarding the importance of amphibians and their symbiotic microbiota, detailing the primary research techniques currently employed. Secondly, it discusses the impacts of environmental and biological factors on the characteristics of amphibian symbiotic microbial communities, including dimensions such as altitude, temperature fluctuations, and host dietary habits. Finally, the future directions of research on amphibian symbiotic microbiota are examined, with five recommendations presented: (1) Establish a comprehensive sample library and database of amphibians and their symbiotic microbiota to create a solid foundation for scientific research. (2) Explore the coevolutionary paths between amphibians and symbiotic microbiota to clarify the dynamic evolutionary patterns and principles of their interactions. (3) Strengthen research on specific areas of amphibians, especially the microbial communities in the oral cavity and cloaca. (4) Enhance research on the symbiotic microbiota of the Gymnophiona. (5) Strengthen international cooperation to build cross-border research platforms and jointly promote the rapid development of global amphibian symbiotic microbiology. This article summarizes the current research progress on the interaction between amphibians and their symbiotic microbiota (not necessarily mutualistic). It discusses the conservation of amphibian biodiversity from the perspective of their symbiotic microbial communities and provides a forward-looking analysis of future research directions. It aims to provide rich background information for understanding the complexity of this symbiotic system, while also having significant value in enhancing the effectiveness of amphibian biodiversity conservation.https://www.mdpi.com/2076-2615/15/7/934biodiversityamphibianssymbiotic microbiotagut microbiotaskin microbiota
spellingShingle Ziyi Wang
Yuting Wang
Zhirong He
Siyu Wu
Suyue Wang
Na Zhao
Wei Zhu
Jianping Jiang
Supen Wang
Research Status and Prospect of Amphibian Symbiotic Microbiota
Animals
biodiversity
amphibians
symbiotic microbiota
gut microbiota
skin microbiota
title Research Status and Prospect of Amphibian Symbiotic Microbiota
title_full Research Status and Prospect of Amphibian Symbiotic Microbiota
title_fullStr Research Status and Prospect of Amphibian Symbiotic Microbiota
title_full_unstemmed Research Status and Prospect of Amphibian Symbiotic Microbiota
title_short Research Status and Prospect of Amphibian Symbiotic Microbiota
title_sort research status and prospect of amphibian symbiotic microbiota
topic biodiversity
amphibians
symbiotic microbiota
gut microbiota
skin microbiota
url https://www.mdpi.com/2076-2615/15/7/934
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