Development of mathematical models of synthesis of the O-antigens atoxigenic strains of Vibrio cholerae based on the model of the synthesis of O-antigen secreted in the process of culturing the virulent strain of vibrio сholerae M-41 Ogawa in the production of cholera vaccine
The paper contains the results of the development of mathematical models for O-antigen synthesis by atoxigenic cholera vibrio strains KM 262 biovar El Tor serovar Ogawa, KM 263 biovar El Tor serovar Inaba, and M 377 O139 serogroup based on the modeling of the synthesis of O-antigen, produced in the...
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| Format: | Article |
| Language: | Russian |
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Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»
2018-02-01
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| Series: | Биопрепараты: Профилактика, диагностика, лечение |
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| Online Access: | https://www.biopreparations.ru/jour/article/view/22 |
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| author | A. V. Komissarov O. A. Volokh Yu. A. Aleshina A. K. Nikiforov |
| author_facet | A. V. Komissarov O. A. Volokh Yu. A. Aleshina A. K. Nikiforov |
| author_sort | A. V. Komissarov |
| collection | DOAJ |
| description | The paper contains the results of the development of mathematical models for O-antigen synthesis by atoxigenic cholera vibrio strains KM 262 biovar El Tor serovar Ogawa, KM 263 biovar El Tor serovar Inaba, and M 377 O139 serogroup based on the modeling of the synthesis of O-antigen, produced in the course of cultivation of the virulent Vibrio cholerae M 41 strain belonging to classical biovar, serovar Ogawa. The data obtained provide the possibility to successfully perform the task of up-scaling the designed pilot technology for cultivation of atoxigenic cholera vibrio strains to be utilized on commercial-scale bioreactors. |
| format | Article |
| id | doaj-art-081ff94d7da14063b49d88cc77d7dcaf |
| institution | Kabale University |
| issn | 2221-996X 2619-1156 |
| language | Russian |
| publishDate | 2018-02-01 |
| publisher | Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» |
| record_format | Article |
| series | Биопрепараты: Профилактика, диагностика, лечение |
| spelling | doaj-art-081ff94d7da14063b49d88cc77d7dcaf2025-08-20T03:43:15ZrusMinistry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»Биопрепараты: Профилактика, диагностика, лечение2221-996X2619-11562018-02-0103545722Development of mathematical models of synthesis of the O-antigens atoxigenic strains of Vibrio cholerae based on the model of the synthesis of O-antigen secreted in the process of culturing the virulent strain of vibrio сholerae M-41 Ogawa in the production of cholera vaccineA. V. Komissarov0O. A. Volokh1Yu. A. Aleshina2A. K. Nikiforov3ФКУЗ РосНИПЧИ «Микроб» РоспотребнадзораФКУЗ РосНИПЧИ «Микроб» РоспотребнадзораФКУЗ РосНИПЧИ «Микроб» РоспотребнадзораФКУЗ РосНИПЧИ «Микроб» РоспотребнадзораThe paper contains the results of the development of mathematical models for O-antigen synthesis by atoxigenic cholera vibrio strains KM 262 biovar El Tor serovar Ogawa, KM 263 biovar El Tor serovar Inaba, and M 377 O139 serogroup based on the modeling of the synthesis of O-antigen, produced in the course of cultivation of the virulent Vibrio cholerae M 41 strain belonging to classical biovar, serovar Ogawa. The data obtained provide the possibility to successfully perform the task of up-scaling the designed pilot technology for cultivation of atoxigenic cholera vibrio strains to be utilized on commercial-scale bioreactors.https://www.biopreparations.ru/jour/article/view/22математическая модельо-антигенатоксигенный штаммхолерный вибрионmathematical modelo-antigenatoxigenic strainsvibrio cholerae |
| spellingShingle | A. V. Komissarov O. A. Volokh Yu. A. Aleshina A. K. Nikiforov Development of mathematical models of synthesis of the O-antigens atoxigenic strains of Vibrio cholerae based on the model of the synthesis of O-antigen secreted in the process of culturing the virulent strain of vibrio сholerae M-41 Ogawa in the production of cholera vaccine Биопрепараты: Профилактика, диагностика, лечение математическая модель о-антиген атоксигенный штамм холерный вибрион mathematical model o-antigen atoxigenic strains vibrio cholerae |
| title | Development of mathematical models of synthesis of the O-antigens atoxigenic strains of Vibrio cholerae based on the model of the synthesis of O-antigen secreted in the process of culturing the virulent strain of vibrio сholerae M-41 Ogawa in the production of cholera vaccine |
| title_full | Development of mathematical models of synthesis of the O-antigens atoxigenic strains of Vibrio cholerae based on the model of the synthesis of O-antigen secreted in the process of culturing the virulent strain of vibrio сholerae M-41 Ogawa in the production of cholera vaccine |
| title_fullStr | Development of mathematical models of synthesis of the O-antigens atoxigenic strains of Vibrio cholerae based on the model of the synthesis of O-antigen secreted in the process of culturing the virulent strain of vibrio сholerae M-41 Ogawa in the production of cholera vaccine |
| title_full_unstemmed | Development of mathematical models of synthesis of the O-antigens atoxigenic strains of Vibrio cholerae based on the model of the synthesis of O-antigen secreted in the process of culturing the virulent strain of vibrio сholerae M-41 Ogawa in the production of cholera vaccine |
| title_short | Development of mathematical models of synthesis of the O-antigens atoxigenic strains of Vibrio cholerae based on the model of the synthesis of O-antigen secreted in the process of culturing the virulent strain of vibrio сholerae M-41 Ogawa in the production of cholera vaccine |
| title_sort | development of mathematical models of synthesis of the o antigens atoxigenic strains of vibrio cholerae based on the model of the synthesis of o antigen secreted in the process of culturing the virulent strain of vibrio сholerae m 41 ogawa in the production of cholera vaccine |
| topic | математическая модель о-антиген атоксигенный штамм холерный вибрион mathematical model o-antigen atoxigenic strains vibrio cholerae |
| url | https://www.biopreparations.ru/jour/article/view/22 |
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