Sarcoidosis with Major Airway, Vascular and Nerve Compromise
The present report describes a 60-year-old Caucasian woman who presented with progressive dyspnea, cough and wheeze. A computed tomography scan of the chest showed innumerable bilateral inflammatory pulmonary nodules with bronchovascular distribution and a mediastinal and hilar infiltrative process...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
|
| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/273535 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832560085457436672 |
|---|---|
| author | Hiroshi Sekiguchi Jun Suzuki James P Utz |
| author_facet | Hiroshi Sekiguchi Jun Suzuki James P Utz |
| author_sort | Hiroshi Sekiguchi |
| collection | DOAJ |
| description | The present report describes a 60-year-old Caucasian woman who presented with progressive dyspnea, cough and wheeze. A computed tomography scan of the chest showed innumerable bilateral inflammatory pulmonary nodules with bronchovascular distribution and a mediastinal and hilar infiltrative process with calcified lymphadenopathy leading to narrowing of lobar bronchi and pulmonary arteries. An echocardiogram revealed pulmonary hypertension. Bronchoscopy showed left vocal cord paralysis and significant narrowing of the bilateral bronchi with mucosal thickening and multiple nodules. Transbronchial biopsy was compatible with sarcoidosis. Despite balloon angioplasty of the left lower lobe and pulmonary artery, and medical therapy with oral corticosteroids, her symptoms did not significantly improve. To the authors’ knowledge, the present report describes the first case of pulmonary sarcoidosis resulting in major airway, vascular and nerve compromise due to compressive lymphadenopathy and suspected concurrent granulomatous infiltration. Its presentation mimicked idiopathic mediastinal fibrosis. |
| format | Article |
| id | doaj-art-0817d5fa7d35422db40ae81680e54dcd |
| institution | Kabale University |
| issn | 1198-2241 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-0817d5fa7d35422db40ae81680e54dcd2025-02-03T01:28:25ZengWileyCanadian Respiratory Journal1198-22412013-01-0120425625810.1155/2013/273535Sarcoidosis with Major Airway, Vascular and Nerve CompromiseHiroshi Sekiguchi0Jun Suzuki1James P Utz2Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USADivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USADivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USAThe present report describes a 60-year-old Caucasian woman who presented with progressive dyspnea, cough and wheeze. A computed tomography scan of the chest showed innumerable bilateral inflammatory pulmonary nodules with bronchovascular distribution and a mediastinal and hilar infiltrative process with calcified lymphadenopathy leading to narrowing of lobar bronchi and pulmonary arteries. An echocardiogram revealed pulmonary hypertension. Bronchoscopy showed left vocal cord paralysis and significant narrowing of the bilateral bronchi with mucosal thickening and multiple nodules. Transbronchial biopsy was compatible with sarcoidosis. Despite balloon angioplasty of the left lower lobe and pulmonary artery, and medical therapy with oral corticosteroids, her symptoms did not significantly improve. To the authors’ knowledge, the present report describes the first case of pulmonary sarcoidosis resulting in major airway, vascular and nerve compromise due to compressive lymphadenopathy and suspected concurrent granulomatous infiltration. Its presentation mimicked idiopathic mediastinal fibrosis.http://dx.doi.org/10.1155/2013/273535 |
| spellingShingle | Hiroshi Sekiguchi Jun Suzuki James P Utz Sarcoidosis with Major Airway, Vascular and Nerve Compromise Canadian Respiratory Journal |
| title | Sarcoidosis with Major Airway, Vascular and Nerve Compromise |
| title_full | Sarcoidosis with Major Airway, Vascular and Nerve Compromise |
| title_fullStr | Sarcoidosis with Major Airway, Vascular and Nerve Compromise |
| title_full_unstemmed | Sarcoidosis with Major Airway, Vascular and Nerve Compromise |
| title_short | Sarcoidosis with Major Airway, Vascular and Nerve Compromise |
| title_sort | sarcoidosis with major airway vascular and nerve compromise |
| url | http://dx.doi.org/10.1155/2013/273535 |
| work_keys_str_mv | AT hiroshisekiguchi sarcoidosiswithmajorairwayvascularandnervecompromise AT junsuzuki sarcoidosiswithmajorairwayvascularandnervecompromise AT jamesputz sarcoidosiswithmajorairwayvascularandnervecompromise |