SIRT1 and SIRT2: emerging targets in neurodegeneration
Abstract Sirtuins are NAD‐dependent protein deacetylases known to have protective effects against age‐related diseases such as cancer, diabetes, cardiovascular and neurodegenerative diseases. In mammals, there are seven sirtuins (SIRT1‐7), which display diversity in subcellular localization and func...
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| Main Authors: | Gizem Donmez, Tiago F. Outeiro |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2013-02-01
|
| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/emmm.201302451 |
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