PULMONARY AND LIVER DAMAGE DURING TREATMENT WITH ACETAMINOPHEN (PARACETAMOL)
This is a case report of pulmonary damage in the form of intestinal pneumonitis with severe respiratory failure during administration of acetaminophen (paracetamol). In addition, significant increase of ALT and AST levels without clinical signs of liver damage was observed in this patient. After glu...
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| Format: | Article |
| Language: | Russian |
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SINAPS LLC
2016-08-01
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| Series: | Архивъ внутренней медицины |
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| Online Access: | https://www.medarhive.ru/jour/article/view/555 |
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| author | L. I. Dvoretski A. N. Kovalevskaja S. E. Kolendo E. V. Sergeeva |
| author_facet | L. I. Dvoretski A. N. Kovalevskaja S. E. Kolendo E. V. Sergeeva |
| author_sort | L. I. Dvoretski |
| collection | DOAJ |
| description | This is a case report of pulmonary damage in the form of intestinal pneumonitis with severe respiratory failure during administration of acetaminophen (paracetamol). In addition, significant increase of ALT and AST levels without clinical signs of liver damage was observed in this patient. After glucocorticoids administration regression of radiological abnormal findings in the lungs along with normalization of liver enzymes values were registered. The rarity of interstitial pneumonitis induced by acetaminophen (paracetamol), especially in combination with liver damage, is emphasized. The presented patient history is the first case report of drug-induced hepatopulmonary syndrome during acetaminophen (paracetamol) administration. |
| format | Article |
| id | doaj-art-080fb90c1e324f9185151a213a58d536 |
| institution | Kabale University |
| issn | 2226-6704 2411-6564 |
| language | Russian |
| publishDate | 2016-08-01 |
| publisher | SINAPS LLC |
| record_format | Article |
| series | Архивъ внутренней медицины |
| spelling | doaj-art-080fb90c1e324f9185151a213a58d5362025-08-20T04:00:03ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642016-08-0164586410.20514/2226-6704-2016-6-4-58-64537PULMONARY AND LIVER DAMAGE DURING TREATMENT WITH ACETAMINOPHEN (PARACETAMOL)L. I. Dvoretski0A. N. Kovalevskaja1S. E. Kolendo2E. V. Sergeeva3The First Moscow State Medical University n. I.M. Sechenov, Moscow, Russia City Clinical Hospital n. S.S. Yudin, DHM, Moscow, RussiaThe First Moscow State Medical University n. I.M. Sechenov, Moscow, Russia City Clinical Hospital n. S.S. Yudin, DHM, Moscow, RussiaThe First Moscow State Medical University n. I.M. Sechenov, Moscow, Russia City Clinical Hospital n. S.S. Yudin, DHM, Moscow, RussiaThe First Moscow State Medical University n. I.M. Sechenov, Moscow, Russia City Clinical Hospital n. S.S. Yudin, DHM, Moscow, RussiaThis is a case report of pulmonary damage in the form of intestinal pneumonitis with severe respiratory failure during administration of acetaminophen (paracetamol). In addition, significant increase of ALT and AST levels without clinical signs of liver damage was observed in this patient. After glucocorticoids administration regression of radiological abnormal findings in the lungs along with normalization of liver enzymes values were registered. The rarity of interstitial pneumonitis induced by acetaminophen (paracetamol), especially in combination with liver damage, is emphasized. The presented patient history is the first case report of drug-induced hepatopulmonary syndrome during acetaminophen (paracetamol) administration.https://www.medarhive.ru/jour/article/view/555acetaminopheninterstitial pneumonitisalanine aminotransferase (alt)aspartate aminotransferase (ast) |
| spellingShingle | L. I. Dvoretski A. N. Kovalevskaja S. E. Kolendo E. V. Sergeeva PULMONARY AND LIVER DAMAGE DURING TREATMENT WITH ACETAMINOPHEN (PARACETAMOL) Архивъ внутренней медицины acetaminophen interstitial pneumonitis alanine aminotransferase (alt) aspartate aminotransferase (ast) |
| title | PULMONARY AND LIVER DAMAGE DURING TREATMENT WITH ACETAMINOPHEN (PARACETAMOL) |
| title_full | PULMONARY AND LIVER DAMAGE DURING TREATMENT WITH ACETAMINOPHEN (PARACETAMOL) |
| title_fullStr | PULMONARY AND LIVER DAMAGE DURING TREATMENT WITH ACETAMINOPHEN (PARACETAMOL) |
| title_full_unstemmed | PULMONARY AND LIVER DAMAGE DURING TREATMENT WITH ACETAMINOPHEN (PARACETAMOL) |
| title_short | PULMONARY AND LIVER DAMAGE DURING TREATMENT WITH ACETAMINOPHEN (PARACETAMOL) |
| title_sort | pulmonary and liver damage during treatment with acetaminophen paracetamol |
| topic | acetaminophen interstitial pneumonitis alanine aminotransferase (alt) aspartate aminotransferase (ast) |
| url | https://www.medarhive.ru/jour/article/view/555 |
| work_keys_str_mv | AT lidvoretski pulmonaryandliverdamageduringtreatmentwithacetaminophenparacetamol AT ankovalevskaja pulmonaryandliverdamageduringtreatmentwithacetaminophenparacetamol AT sekolendo pulmonaryandliverdamageduringtreatmentwithacetaminophenparacetamol AT evsergeeva pulmonaryandliverdamageduringtreatmentwithacetaminophenparacetamol |