Recurrent Migratory Transient Bone Marrow Edema of the Knees Associated with Low Vitamin D and Systemic Low Bone Mineral Density: A Case Report and Literature Review

Transient bone marrow edema (TBME) is a self-limiting disease characterized by joint pain with localized bone marrow edema by MRI and has been reported in many case series and case reports. It is well known that joints of the lower extremity including hips, knees, ankles, and feet are the classical...

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Main Authors: Omar Alsaed, Mohammad Hammoudeh
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2018/7657982
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author Omar Alsaed
Mohammad Hammoudeh
author_facet Omar Alsaed
Mohammad Hammoudeh
author_sort Omar Alsaed
collection DOAJ
description Transient bone marrow edema (TBME) is a self-limiting disease characterized by joint pain with localized bone marrow edema by MRI and has been reported in many case series and case reports. It is well known that joints of the lower extremity including hips, knees, ankles, and feet are the classical sites for TBME. Many theories have been proposed for the pathogenesis of TBME. Systemic osteopenia and vitamin D deficiency is one of the theories that have been suggested in the last few years. In this case report, we present a middle-aged male patient, who presented with 4 attacks of TBME in both knees between September 2016 and August 2017. The patient was found to have persistently low vitamin D and osteopenic T score in DXA scan of the lumbar spine and hips. Patients of TBME usually present with joint pain that is provoked by weight-bearing physical activity. The aim of this case report is to raise the awareness that TBME can be the initial presentation of systemic loss of bone mineral density.
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issn 2090-6889
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publishDate 2018-01-01
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spelling doaj-art-0802f9b604894415b06a8856dc1dd15e2025-08-20T03:55:28ZengWileyCase Reports in Rheumatology2090-68892090-68972018-01-01201810.1155/2018/76579827657982Recurrent Migratory Transient Bone Marrow Edema of the Knees Associated with Low Vitamin D and Systemic Low Bone Mineral Density: A Case Report and Literature ReviewOmar Alsaed0Mohammad Hammoudeh1Hamad Medical Corporation, Hamad General Hospital, Rheumatology Section, P.O. Box 3050, Doha, QatarHamad Medical Corporation, Hamad General Hospital, Rheumatology Section, P.O. Box 3050, Doha, QatarTransient bone marrow edema (TBME) is a self-limiting disease characterized by joint pain with localized bone marrow edema by MRI and has been reported in many case series and case reports. It is well known that joints of the lower extremity including hips, knees, ankles, and feet are the classical sites for TBME. Many theories have been proposed for the pathogenesis of TBME. Systemic osteopenia and vitamin D deficiency is one of the theories that have been suggested in the last few years. In this case report, we present a middle-aged male patient, who presented with 4 attacks of TBME in both knees between September 2016 and August 2017. The patient was found to have persistently low vitamin D and osteopenic T score in DXA scan of the lumbar spine and hips. Patients of TBME usually present with joint pain that is provoked by weight-bearing physical activity. The aim of this case report is to raise the awareness that TBME can be the initial presentation of systemic loss of bone mineral density.http://dx.doi.org/10.1155/2018/7657982
spellingShingle Omar Alsaed
Mohammad Hammoudeh
Recurrent Migratory Transient Bone Marrow Edema of the Knees Associated with Low Vitamin D and Systemic Low Bone Mineral Density: A Case Report and Literature Review
Case Reports in Rheumatology
title Recurrent Migratory Transient Bone Marrow Edema of the Knees Associated with Low Vitamin D and Systemic Low Bone Mineral Density: A Case Report and Literature Review
title_full Recurrent Migratory Transient Bone Marrow Edema of the Knees Associated with Low Vitamin D and Systemic Low Bone Mineral Density: A Case Report and Literature Review
title_fullStr Recurrent Migratory Transient Bone Marrow Edema of the Knees Associated with Low Vitamin D and Systemic Low Bone Mineral Density: A Case Report and Literature Review
title_full_unstemmed Recurrent Migratory Transient Bone Marrow Edema of the Knees Associated with Low Vitamin D and Systemic Low Bone Mineral Density: A Case Report and Literature Review
title_short Recurrent Migratory Transient Bone Marrow Edema of the Knees Associated with Low Vitamin D and Systemic Low Bone Mineral Density: A Case Report and Literature Review
title_sort recurrent migratory transient bone marrow edema of the knees associated with low vitamin d and systemic low bone mineral density a case report and literature review
url http://dx.doi.org/10.1155/2018/7657982
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AT mohammadhammoudeh recurrentmigratorytransientbonemarrowedemaofthekneesassociatedwithlowvitamindandsystemiclowbonemineraldensityacasereportandliteraturereview