Mechanisms of Influence of Methicillin Resistant Staphylococcus Aureus on Functional State of Neutrophilic Granulocytes
The aim of the study was to estimate the functional activity of neutrophilic granulocytes after the contact with MSSA and MRSA. It was determined by luminol-dependent chemoluminescence with stimulation by the priming doses of MRSA and MSSA. The functional activity of neutrophilic granulocytes was sh...
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| Format: | Article |
| Language: | Russian |
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LLC "Publishing House OKI"
2020-05-01
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| Series: | Антибиотики и Химиотерапия |
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| Online Access: | https://www.antibiotics-chemotherapy.ru/jour/article/view/575 |
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| author | O. A. Kolenchukova N. I. Sarmatova |
| author_facet | O. A. Kolenchukova N. I. Sarmatova |
| author_sort | O. A. Kolenchukova |
| collection | DOAJ |
| description | The aim of the study was to estimate the functional activity of neutrophilic granulocytes after the contact with MSSA and MRSA. It was determined by luminol-dependent chemoluminescence with stimulation by the priming doses of MRSA and MSSA. The functional activity of neutrophilic granulocytes was shown to increase in response to either the resistant Staphylococcus aureus strains or the susceptible ones. It should be indicated that the intensity of the oxygen-dependent phagocytosis in response to MRSA was higher than that to MSSA. |
| format | Article |
| id | doaj-art-080291ad775f45a4874063399d2ee010 |
| institution | DOAJ |
| issn | 0235-2990 |
| language | Russian |
| publishDate | 2020-05-01 |
| publisher | LLC "Publishing House OKI" |
| record_format | Article |
| series | Антибиотики и Химиотерапия |
| spelling | doaj-art-080291ad775f45a4874063399d2ee0102025-08-20T02:49:36ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-015911-122023574Mechanisms of Influence of Methicillin Resistant Staphylococcus Aureus on Functional State of Neutrophilic GranulocytesO. A. Kolenchukova0N. I. Sarmatova1Research Institute of Medical Problems of the North, Krasnoyarsk Siberian Federal UniversityResearch Institute of Medical Problems of the North, Krasnoyarsk Siberian Federal UniversityThe aim of the study was to estimate the functional activity of neutrophilic granulocytes after the contact with MSSA and MRSA. It was determined by luminol-dependent chemoluminescence with stimulation by the priming doses of MRSA and MSSA. The functional activity of neutrophilic granulocytes was shown to increase in response to either the resistant Staphylococcus aureus strains or the susceptible ones. It should be indicated that the intensity of the oxygen-dependent phagocytosis in response to MRSA was higher than that to MSSA.https://www.antibiotics-chemotherapy.ru/jour/article/view/575mrsamssamrsamssaneutrophilic granulocytes |
| spellingShingle | O. A. Kolenchukova N. I. Sarmatova Mechanisms of Influence of Methicillin Resistant Staphylococcus Aureus on Functional State of Neutrophilic Granulocytes Антибиотики и Химиотерапия mrsa mssa mrsa mssa neutrophilic granulocytes |
| title | Mechanisms of Influence of Methicillin Resistant Staphylococcus Aureus on Functional State of Neutrophilic Granulocytes |
| title_full | Mechanisms of Influence of Methicillin Resistant Staphylococcus Aureus on Functional State of Neutrophilic Granulocytes |
| title_fullStr | Mechanisms of Influence of Methicillin Resistant Staphylococcus Aureus on Functional State of Neutrophilic Granulocytes |
| title_full_unstemmed | Mechanisms of Influence of Methicillin Resistant Staphylococcus Aureus on Functional State of Neutrophilic Granulocytes |
| title_short | Mechanisms of Influence of Methicillin Resistant Staphylococcus Aureus on Functional State of Neutrophilic Granulocytes |
| title_sort | mechanisms of influence of methicillin resistant staphylococcus aureus on functional state of neutrophilic granulocytes |
| topic | mrsa mssa mrsa mssa neutrophilic granulocytes |
| url | https://www.antibiotics-chemotherapy.ru/jour/article/view/575 |
| work_keys_str_mv | AT oakolenchukova mechanismsofinfluenceofmethicillinresistantstaphylococcusaureusonfunctionalstateofneutrophilicgranulocytes AT nisarmatova mechanismsofinfluenceofmethicillinresistantstaphylococcusaureusonfunctionalstateofneutrophilicgranulocytes |