Spot Versus 24-Hour Urine Osmolality Measurement in Autosomal Dominant Polycystic Kidney Disease: A Diagnostic Test Study

Spot Versus 24-Hour Urine Osmolality Measurement in Autosomal Dominant Polycystic Kidney Disease: A Diagnostic Test Study

Rationale & Objective: Arginine vasopressin (AVP) is an established driver of cyst growth in autosomal dominant polycystic kidney disease (ADPKD). Urine osmolality (osm) measures are surrogate markers of AVP activity. Both 24-hour and spot urine samples are used as indicators of AVP suppress...

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Bibliographic Details
Main Authors: Ayub Akbari, Sriram Sriperumbuduri, Shreepryia Mangalgi, Vijay Joshi, Manish Sood, Amos Buh, Mohan Biyani, Christopher McCudden, Gregory L. Hundemer, Pierre Antoine Brown
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Kidney Medicine
Subjects:
Urine osmolarity
spot and 24-hour measurement
autosomal dominant polycystic kidney disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2590059525000019
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