Implantable Multifunctional Micro‐Oxygen Reservoir System for Promoting Vascular‐Osteogenesis via Remodeling Regenerative Microenvironment

Implantable Multifunctional Micro‐Oxygen Reservoir System for Promoting Vascular‐Osteogenesis via Remodeling Regenerative Microenvironment

Abstract Hypoxia and reactive oxygen species (ROS) overaccumulation cause persistent oxidative stress and impair intrinsic regenerative potential upon tissue injury. For local tissue injury with hypoxia, such as bone fracture and defects, a localized‐sufficient oxygen supply is highly desirable but...

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Bibliographic Details
Main Authors: Min Rui, Jiannan Mao, Hongshuai Wu, Yujian Hui, Hao Shen, Yilin Yang, Tao Ma, Kewei Ren, Juan Wang, Wenguo Cui, Qin Shi, Huilin Yang
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
bone regeneration
hydrogel microsphere
hypoxia
microenvironment regulation
oxygen generation
reactive oxygen species
Online Access:https://doi.org/10.1002/advs.202409636
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