Congenital Insensitivity to Pain With Anhidrosis: First Reported Case in Nepal
ABSTRACT Congenital insensitivity to pain with anhidrosis is a rare autosomal recessive disorder characterized by anhidrosis, self‐mutilation, and insensitivity to pain and temperature. While genetic testing confirms the diagnosis, it is not always feasible, making clinical recognition crucial in re...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2025-08-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.70697 |
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| _version_ | 1849229068008947712 |
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| author | Sobin Pant Dibij Adhikari Prakash Pandey Binit Bajracharya Rizuna Sharma |
| author_facet | Sobin Pant Dibij Adhikari Prakash Pandey Binit Bajracharya Rizuna Sharma |
| author_sort | Sobin Pant |
| collection | DOAJ |
| description | ABSTRACT Congenital insensitivity to pain with anhidrosis is a rare autosomal recessive disorder characterized by anhidrosis, self‐mutilation, and insensitivity to pain and temperature. While genetic testing confirms the diagnosis, it is not always feasible, making clinical recognition crucial in resource‐limited settings. Early diagnosis and a multidisciplinary approach help prevent complications like severe injuries, infections, and hyperpyrexia. |
| format | Article |
| id | doaj-art-07f566c5dd1a49e8ab9fa058fda548f4 |
| institution | Kabale University |
| issn | 2050-0904 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj-art-07f566c5dd1a49e8ab9fa058fda548f42025-08-22T07:33:07ZengWileyClinical Case Reports2050-09042025-08-01138n/an/a10.1002/ccr3.70697Congenital Insensitivity to Pain With Anhidrosis: First Reported Case in NepalSobin Pant0Dibij Adhikari1Prakash Pandey2Binit Bajracharya3Rizuna Sharma4Maharajgunj Medical Campus, Institute of Medicine Tribhuvan University Kathmandu NepalMaharajgunj Medical Campus, Institute of Medicine Tribhuvan University Kathmandu NepalMaharajgunj Medical Campus, Institute of Medicine Tribhuvan University Kathmandu NepalMaharajgunj Medical Campus, Institute of Medicine Tribhuvan University Kathmandu NepalDepartment of Pediatrics Tribhuvan University Teaching Hospital Kathmandu NepalABSTRACT Congenital insensitivity to pain with anhidrosis is a rare autosomal recessive disorder characterized by anhidrosis, self‐mutilation, and insensitivity to pain and temperature. While genetic testing confirms the diagnosis, it is not always feasible, making clinical recognition crucial in resource‐limited settings. Early diagnosis and a multidisciplinary approach help prevent complications like severe injuries, infections, and hyperpyrexia.https://doi.org/10.1002/ccr3.70697anhidrosiscongenital insensitivity to pain with anhidrosishereditary sensory and autonomic neuropathy type IVpain insensitivityresource‐limited settingsself‐mutilation |
| spellingShingle | Sobin Pant Dibij Adhikari Prakash Pandey Binit Bajracharya Rizuna Sharma Congenital Insensitivity to Pain With Anhidrosis: First Reported Case in Nepal Clinical Case Reports anhidrosis congenital insensitivity to pain with anhidrosis hereditary sensory and autonomic neuropathy type IV pain insensitivity resource‐limited settings self‐mutilation |
| title | Congenital Insensitivity to Pain With Anhidrosis: First Reported Case in Nepal |
| title_full | Congenital Insensitivity to Pain With Anhidrosis: First Reported Case in Nepal |
| title_fullStr | Congenital Insensitivity to Pain With Anhidrosis: First Reported Case in Nepal |
| title_full_unstemmed | Congenital Insensitivity to Pain With Anhidrosis: First Reported Case in Nepal |
| title_short | Congenital Insensitivity to Pain With Anhidrosis: First Reported Case in Nepal |
| title_sort | congenital insensitivity to pain with anhidrosis first reported case in nepal |
| topic | anhidrosis congenital insensitivity to pain with anhidrosis hereditary sensory and autonomic neuropathy type IV pain insensitivity resource‐limited settings self‐mutilation |
| url | https://doi.org/10.1002/ccr3.70697 |
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