Invasive Aspergillosis in the Intensive Care Unit

Invasive aspergillosis (IA) is a fungal infection, which has traditionally been associated with neutropenia and immunosuppressive therapies. Our understanding of invasive aspergillosis has been evolving and, in the past few decades, IA among ICU patients has been recognized as a common infection and...

Full description

Saved in:
Bibliographic Details
Main Authors: Anna Zubovskaia, Jose A. Vazquez
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Journal of Fungi
Subjects:
Online Access:https://www.mdpi.com/2309-608X/11/1/70
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832588176170942464
author Anna Zubovskaia
Jose A. Vazquez
author_facet Anna Zubovskaia
Jose A. Vazquez
author_sort Anna Zubovskaia
collection DOAJ
description Invasive aspergillosis (IA) is a fungal infection, which has traditionally been associated with neutropenia and immunosuppressive therapies. Our understanding of invasive aspergillosis has been evolving and, in the past few decades, IA among ICU patients has been recognized as a common infection and has become more widely recognized. The diagnosis and management of invasive aspergillosis in the ICU is particularly challenging, due to the unstable clinical condition of the patients, lack of diagnostic markers, increased risk of further clinical deterioration, multiple comorbidities, and a need for early assessment and treatment. In this article, we will discuss the challenges and pitfalls of the diagnosis and management of invasive aspergillosis in an ICU setting, along with a review of the current literature that is pertinent and specific to this population.
format Article
id doaj-art-07ec04b4b2d64237a6ce4b95e926778d
institution Kabale University
issn 2309-608X
language English
publishDate 2025-01-01
publisher MDPI AG
record_format Article
series Journal of Fungi
spelling doaj-art-07ec04b4b2d64237a6ce4b95e926778d2025-01-24T13:37:26ZengMDPI AGJournal of Fungi2309-608X2025-01-011117010.3390/jof11010070Invasive Aspergillosis in the Intensive Care UnitAnna Zubovskaia0Jose A. Vazquez1Division of Infectious Diseases, Medical College of Georgia, Augusta University, Augusta, GA 30912, USADivision of Infectious Diseases, Medical College of Georgia, Augusta University, Augusta, GA 30912, USAInvasive aspergillosis (IA) is a fungal infection, which has traditionally been associated with neutropenia and immunosuppressive therapies. Our understanding of invasive aspergillosis has been evolving and, in the past few decades, IA among ICU patients has been recognized as a common infection and has become more widely recognized. The diagnosis and management of invasive aspergillosis in the ICU is particularly challenging, due to the unstable clinical condition of the patients, lack of diagnostic markers, increased risk of further clinical deterioration, multiple comorbidities, and a need for early assessment and treatment. In this article, we will discuss the challenges and pitfalls of the diagnosis and management of invasive aspergillosis in an ICU setting, along with a review of the current literature that is pertinent and specific to this population.https://www.mdpi.com/2309-608X/11/1/70aspergillosisintensive care unitinvasive aspergillosisantifungals
spellingShingle Anna Zubovskaia
Jose A. Vazquez
Invasive Aspergillosis in the Intensive Care Unit
Journal of Fungi
aspergillosis
intensive care unit
invasive aspergillosis
antifungals
title Invasive Aspergillosis in the Intensive Care Unit
title_full Invasive Aspergillosis in the Intensive Care Unit
title_fullStr Invasive Aspergillosis in the Intensive Care Unit
title_full_unstemmed Invasive Aspergillosis in the Intensive Care Unit
title_short Invasive Aspergillosis in the Intensive Care Unit
title_sort invasive aspergillosis in the intensive care unit
topic aspergillosis
intensive care unit
invasive aspergillosis
antifungals
url https://www.mdpi.com/2309-608X/11/1/70
work_keys_str_mv AT annazubovskaia invasiveaspergillosisintheintensivecareunit
AT joseavazquez invasiveaspergillosisintheintensivecareunit