OPPORTUNITIES TO DIAGNOSE ACTIVE TUBERCULOSIS IN THE PATIENTS WITH CLINICALLY CURED RESPIRATORY TUBERCULOSIS

Goal of the study: to evaluate the test with tuberculous recombinant allergen (TRA) in the patients with effective treatment course due to tuberculosis, to investigate the impact of clinical, epidemiological and social factors on persistence of active tuberculosis.Materials and methods. Patients wer...

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Main Authors: G. S. Balasanyants, N. S. Skotnikova
Format: Article
Language:Russian
Published: New Terra Publishing House 2017-04-01
Series:Туберкулез и болезни лёгких
Subjects:
Online Access:https://www.tibl-journal.com/jour/article/view/994
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author G. S. Balasanyants
N. S. Skotnikova
author_facet G. S. Balasanyants
N. S. Skotnikova
author_sort G. S. Balasanyants
collection DOAJ
description Goal of the study: to evaluate the test with tuberculous recombinant allergen (TRA) in the patients with effective treatment course due to tuberculosis, to investigate the impact of clinical, epidemiological and social factors on persistence of active tuberculosis.Materials and methods. Patients were divided into 2 groups basing on time period after completion of the main treatment course. Group I – 32 patients (up to 6 months), group II – 63 patients (more than 6 months).Results of the study. Results of TRA tests in Group I remained positive in 34.4% of patients and in Group II - 23.8%. The average size of the induration in Group I made 10 mm(95% CI 6.5-13.3), in Group II – 13 mm (95% CI 8.4-19.7) Patients from Group I had positive results of TRA test more often in case of initial infiltrate form of pulmonary tuberculosis and bacillary excretion. In patients from Group II the positive TRA results correlated with presence of concurrent conditions and exposure to a tuberculosis case in the past. Positive results were confidently more often observed in lonely patients in both groups. TRA test can be a valuable tool to evaluate the risk of tuberculosis relapse after completion of the main treatment course.
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issn 2075-1230
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series Туберкулез и болезни лёгких
spelling doaj-art-07d4669aa13141c5bad114d2bc523fbb2025-08-20T02:05:56ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062017-04-01954374410.21292/2075-1230-2017-95-4-37-44994OPPORTUNITIES TO DIAGNOSE ACTIVE TUBERCULOSIS IN THE PATIENTS WITH CLINICALLY CURED RESPIRATORY TUBERCULOSISG. S. Balasanyants0N. S. Skotnikova1S. M. Kirov Military Medical AcademyTB Dispensary no. 5Goal of the study: to evaluate the test with tuberculous recombinant allergen (TRA) in the patients with effective treatment course due to tuberculosis, to investigate the impact of clinical, epidemiological and social factors on persistence of active tuberculosis.Materials and methods. Patients were divided into 2 groups basing on time period after completion of the main treatment course. Group I – 32 patients (up to 6 months), group II – 63 patients (more than 6 months).Results of the study. Results of TRA tests in Group I remained positive in 34.4% of patients and in Group II - 23.8%. The average size of the induration in Group I made 10 mm(95% CI 6.5-13.3), in Group II – 13 mm (95% CI 8.4-19.7) Patients from Group I had positive results of TRA test more often in case of initial infiltrate form of pulmonary tuberculosis and bacillary excretion. In patients from Group II the positive TRA results correlated with presence of concurrent conditions and exposure to a tuberculosis case in the past. Positive results were confidently more often observed in lonely patients in both groups. TRA test can be a valuable tool to evaluate the risk of tuberculosis relapse after completion of the main treatment course.https://www.tibl-journal.com/jour/article/view/994pulmonary tuberculosislatent tuberculous infectionrelapsediagnosticsskin test with recombinant tuberculous allergen
spellingShingle G. S. Balasanyants
N. S. Skotnikova
OPPORTUNITIES TO DIAGNOSE ACTIVE TUBERCULOSIS IN THE PATIENTS WITH CLINICALLY CURED RESPIRATORY TUBERCULOSIS
Туберкулез и болезни лёгких
pulmonary tuberculosis
latent tuberculous infection
relapse
diagnostics
skin test with recombinant tuberculous allergen
title OPPORTUNITIES TO DIAGNOSE ACTIVE TUBERCULOSIS IN THE PATIENTS WITH CLINICALLY CURED RESPIRATORY TUBERCULOSIS
title_full OPPORTUNITIES TO DIAGNOSE ACTIVE TUBERCULOSIS IN THE PATIENTS WITH CLINICALLY CURED RESPIRATORY TUBERCULOSIS
title_fullStr OPPORTUNITIES TO DIAGNOSE ACTIVE TUBERCULOSIS IN THE PATIENTS WITH CLINICALLY CURED RESPIRATORY TUBERCULOSIS
title_full_unstemmed OPPORTUNITIES TO DIAGNOSE ACTIVE TUBERCULOSIS IN THE PATIENTS WITH CLINICALLY CURED RESPIRATORY TUBERCULOSIS
title_short OPPORTUNITIES TO DIAGNOSE ACTIVE TUBERCULOSIS IN THE PATIENTS WITH CLINICALLY CURED RESPIRATORY TUBERCULOSIS
title_sort opportunities to diagnose active tuberculosis in the patients with clinically cured respiratory tuberculosis
topic pulmonary tuberculosis
latent tuberculous infection
relapse
diagnostics
skin test with recombinant tuberculous allergen
url https://www.tibl-journal.com/jour/article/view/994
work_keys_str_mv AT gsbalasanyants opportunitiestodiagnoseactivetuberculosisinthepatientswithclinicallycuredrespiratorytuberculosis
AT nsskotnikova opportunitiestodiagnoseactivetuberculosisinthepatientswithclinicallycuredrespiratorytuberculosis