Fetal Primary Cardiac Tumors During Perinatal Period
Fetal primary cardiac tumors are rare, but they may cause complications, which are sometimes life threatening, including arrhythmias, hydrops fetalis, ventricular outflow/inflow obstruction, cardiac failure, and even sudden death. Among fetal primary cardiac tumors, rhabdomyomas are most common, fol...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-06-01
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| Series: | Pediatrics and Neonatology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1875957216302443 |
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| author | Shi-Min Yuan |
| author_facet | Shi-Min Yuan |
| author_sort | Shi-Min Yuan |
| collection | DOAJ |
| description | Fetal primary cardiac tumors are rare, but they may cause complications, which are sometimes life threatening, including arrhythmias, hydrops fetalis, ventricular outflow/inflow obstruction, cardiac failure, and even sudden death. Among fetal primary cardiac tumors, rhabdomyomas are most common, followed by teratomas, fibromas, hemangiomas, and myxomas. Everolimus, a mammalian target of rapamycin inhibitor, has been reported to be an effective drug to cause tumor remission in three neonates with multiple cardiac rhabdomyomas. Neonatal cardiac surgery for the resection of primary cardiac tumors found by fetal echocardiography has been reported sporadically. However, open fetal surgery for pericardial teratoma resection, which was performed successfully via a fetal median sternotomy in one case report, could be a promising intervention to rescue these patients with large pericardial effusions. These recent achievements undoubtedly encourage further development in early management of fetal cardiac tumors. Owing to the rarity of fetal primary cardiac tumors, relevant information in terms of prenatal diagnosis, treatment, and prognosis remains to be clarified. |
| format | Article |
| id | doaj-art-07d29d4082fc40baac8fd6425c52efc9 |
| institution | DOAJ |
| issn | 1875-9572 |
| language | English |
| publishDate | 2017-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj-art-07d29d4082fc40baac8fd6425c52efc92025-08-20T03:16:43ZengElsevierPediatrics and Neonatology1875-95722017-06-0158320521010.1016/j.pedneo.2016.07.004Fetal Primary Cardiac Tumors During Perinatal PeriodShi-Min YuanFetal primary cardiac tumors are rare, but they may cause complications, which are sometimes life threatening, including arrhythmias, hydrops fetalis, ventricular outflow/inflow obstruction, cardiac failure, and even sudden death. Among fetal primary cardiac tumors, rhabdomyomas are most common, followed by teratomas, fibromas, hemangiomas, and myxomas. Everolimus, a mammalian target of rapamycin inhibitor, has been reported to be an effective drug to cause tumor remission in three neonates with multiple cardiac rhabdomyomas. Neonatal cardiac surgery for the resection of primary cardiac tumors found by fetal echocardiography has been reported sporadically. However, open fetal surgery for pericardial teratoma resection, which was performed successfully via a fetal median sternotomy in one case report, could be a promising intervention to rescue these patients with large pericardial effusions. These recent achievements undoubtedly encourage further development in early management of fetal cardiac tumors. Owing to the rarity of fetal primary cardiac tumors, relevant information in terms of prenatal diagnosis, treatment, and prognosis remains to be clarified.http://www.sciencedirect.com/science/article/pii/S1875957216302443heart neoplasmshydrops fetalisprenatal diagnosis |
| spellingShingle | Shi-Min Yuan Fetal Primary Cardiac Tumors During Perinatal Period Pediatrics and Neonatology heart neoplasms hydrops fetalis prenatal diagnosis |
| title | Fetal Primary Cardiac Tumors During Perinatal Period |
| title_full | Fetal Primary Cardiac Tumors During Perinatal Period |
| title_fullStr | Fetal Primary Cardiac Tumors During Perinatal Period |
| title_full_unstemmed | Fetal Primary Cardiac Tumors During Perinatal Period |
| title_short | Fetal Primary Cardiac Tumors During Perinatal Period |
| title_sort | fetal primary cardiac tumors during perinatal period |
| topic | heart neoplasms hydrops fetalis prenatal diagnosis |
| url | http://www.sciencedirect.com/science/article/pii/S1875957216302443 |
| work_keys_str_mv | AT shiminyuan fetalprimarycardiactumorsduringperinatalperiod |