Development and Characterization of Optimized Drug-Loaded Niosomes for Delivery of 5-FU and Irinotecan

Development and Characterization of Optimized Drug-Loaded Niosomes for Delivery of 5-FU and Irinotecan

<b>Background/Objectives</b>: 5-Fluorouracil (5-FU) and Irinotecan (IRT) are two of the most used chemotherapeutic agents in CRC treatment. However, achieving treatment goals has been hampered by poor drug delivery to tumor sites and associated toxicity from off-target binding to healthy...

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Bibliographic Details
Main Authors: Kafilat O. Agbaje, Simeon K. Adesina, Amusa S. Adebayo
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Pharmaceutics
Subjects:
niosomes
5-fluorouracil
Irinotecan
biorelevant dissolution
Online Access:https://www.mdpi.com/1999-4923/17/7/900
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