An Eustachian Tube Neuroendocrine Carcinoma: A Previously Undescribed Entity and Review of the Literature

Primary sinonasal and middle ear neuroendocrine carcinomas are rare malignancies of the head and neck. Owing to the rarity of these tumors, the clinical behavior and optimal management of these tumors are not well defined. We present a case of an incidentally discovered sinonasal neuroendocrine carc...

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Main Authors: Gavin J. le Nobel, Vincent Y. Lin, Vladimir Iakovlev, John M. Lee
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2016/4643615
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author Gavin J. le Nobel
Vincent Y. Lin
Vladimir Iakovlev
John M. Lee
author_facet Gavin J. le Nobel
Vincent Y. Lin
Vladimir Iakovlev
John M. Lee
author_sort Gavin J. le Nobel
collection DOAJ
description Primary sinonasal and middle ear neuroendocrine carcinomas are rare malignancies of the head and neck. Owing to the rarity of these tumors, the clinical behavior and optimal management of these tumors are not well defined. We present a case of an incidentally discovered sinonasal neuroendocrine carcinoma that was found to originate from the Eustachian tube, which has not previously been described in the literature. This patient was treated with primary surgical resection using a combination of transnasal and transaural approaches and achieved an incomplete resection. Follow-up imaging demonstrated continued tumor growth in the Eustachian tube as well as a new growth in the ipsilateral cerebellopontine angle and findings suspicious of perineural invasion. However, the tumor exhibited a benign growth pattern and despite continued growth the patient did not receive additional treatment and he remains asymptomatic 35 months following his original surgery.
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spelling doaj-art-07ae145b49364cfe90930c8baaeba5692025-08-20T02:01:34ZengWileyCase Reports in Surgery2090-69002090-69192016-01-01201610.1155/2016/46436154643615An Eustachian Tube Neuroendocrine Carcinoma: A Previously Undescribed Entity and Review of the LiteratureGavin J. le Nobel0Vincent Y. Lin1Vladimir Iakovlev2John M. Lee3Department of Otolaryngology, Head and Neck Surgery, University of Toronto, Toronto, ON, M5G 2N2, CanadaDepartment of Otolaryngology, Head and Neck Surgery, University of Toronto, Toronto, ON, M5G 2N2, CanadaSt. Michael’s Hospital, Toronto, ON, M5B 1W8, CanadaDepartment of Otolaryngology, Head and Neck Surgery, University of Toronto, Toronto, ON, M5G 2N2, CanadaPrimary sinonasal and middle ear neuroendocrine carcinomas are rare malignancies of the head and neck. Owing to the rarity of these tumors, the clinical behavior and optimal management of these tumors are not well defined. We present a case of an incidentally discovered sinonasal neuroendocrine carcinoma that was found to originate from the Eustachian tube, which has not previously been described in the literature. This patient was treated with primary surgical resection using a combination of transnasal and transaural approaches and achieved an incomplete resection. Follow-up imaging demonstrated continued tumor growth in the Eustachian tube as well as a new growth in the ipsilateral cerebellopontine angle and findings suspicious of perineural invasion. However, the tumor exhibited a benign growth pattern and despite continued growth the patient did not receive additional treatment and he remains asymptomatic 35 months following his original surgery.http://dx.doi.org/10.1155/2016/4643615
spellingShingle Gavin J. le Nobel
Vincent Y. Lin
Vladimir Iakovlev
John M. Lee
An Eustachian Tube Neuroendocrine Carcinoma: A Previously Undescribed Entity and Review of the Literature
Case Reports in Surgery
title An Eustachian Tube Neuroendocrine Carcinoma: A Previously Undescribed Entity and Review of the Literature
title_full An Eustachian Tube Neuroendocrine Carcinoma: A Previously Undescribed Entity and Review of the Literature
title_fullStr An Eustachian Tube Neuroendocrine Carcinoma: A Previously Undescribed Entity and Review of the Literature
title_full_unstemmed An Eustachian Tube Neuroendocrine Carcinoma: A Previously Undescribed Entity and Review of the Literature
title_short An Eustachian Tube Neuroendocrine Carcinoma: A Previously Undescribed Entity and Review of the Literature
title_sort eustachian tube neuroendocrine carcinoma a previously undescribed entity and review of the literature
url http://dx.doi.org/10.1155/2016/4643615
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