A Prospective Observational Comparative study Between qSOFA and SIRS Scores for Early Prediction of Sepsis Outcome in an Emergency Medicine Department , Kozhencherry, South Central Kerala,India

Background Sepsis remains a significant challenge in emergency medicine, with early identification crucial for improved outcomes. The introduction of the quick Sequential Organ Failure Assessment (qSOFA) score has sparked debate about its efficacy compared to the traditional Systemic Infl...

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Main Authors: Rahul Rajeev, , J S Krishna Raj, Anu T R, Pratibha Dabas, Roshni, Seeja Sumedhan
Format: Article
Language:English
Published: Makhdoomi Printers 2025-02-01
Series:Global Journal of Medicine and Public Health
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Online Access:https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4114
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Summary:Background Sepsis remains a significant challenge in emergency medicine, with early identification crucial for improved outcomes. The introduction of the quick Sequential Organ Failure Assessment (qSOFA) score has sparked debate about its efficacy compared to the traditional Systemic Inflammatory Response Syndrome (SIRS) criteria in predicting sepsis outcomes. Objective To compare the performance of qSOFA and SIRS scores in early prediction of sepsis outcomes in an Emergency Medicine Department. Methods A prospective observational study was conducted on 63 patients aged 18-80 years presenting with suspected sepsis at Muthoot Health Care, Kozhencherry. Patients were assessed using both qSOFA and SIRS criteria. Exclusion criteria included pregnancy, terminal illness, and severe comorbidities. Participants were followed up to determine final diagnosis and outcomes. Data analysis compared the effectiveness of qSOFA and SIRS in predicting sepsis outcomes. Results The majority of participants (59.9%) were over 50 years old, with a slight male predominance (54%). qSOFA scores of 0-1 were observed in 55.6% of patients, while 60.3% had SIRS scores of 3-4. The mean qSOFA and SIRS scores were 1.59 and 2.75, respectively. A significant correlation was found between qSOFA scores and outcomes (p=0.007). The in-hospital mortality rate was 30.2%. Conclusion While qSOFA demonstrated a slight advantage in predicting in-hospital mortality, SIRS showed higher sensitivity in sepsis diagnosis. The study suggests that a combined approach using both scoring systems may provide a more comprehensive assessment of patients with suspected sepsis in the emergency department setting. Further large scale, multicenter studies are recommended to validate these findings across diverse populations.  
ISSN:2277-9604