Advances in HIV-1 resistance detection technology

HIV has ravaged the world for more than forty years, causing great pressure on global public health. Today, AIDS is still a medical challenge for global public health. Highly active anti-retroviral therapy (HAART) is the preferred option for AIDS treatment. It has brought well-being to many people l...

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Bibliographic Details
Main Authors: SHEN Kuiling, YAN huimin, LI Lin, LI Hanping
Format: Article
Language:zho
Published: Editorial Office of Journal of Guangxi Medical University 2024-10-01
Series:Guangxi Yike Daxue xuebao
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Online Access:https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2024.10.005
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Summary:HIV has ravaged the world for more than forty years, causing great pressure on global public health. Today, AIDS is still a medical challenge for global public health. Highly active anti-retroviral therapy (HAART) is the preferred option for AIDS treatment. It has brought well-being to many people living with HIV, and has played a great role in slowing the further spread of HIV. However, with the comprehensive application of this therapy program, HIV-1 drug resistance has also become increasingly prominent. HIV-1 drug resistance is one of the main causes affecting the efficacy of clinical antiviral therapy. Therefore, it is very important to carry out HIV-1 drug resistance testing, optimize and select antiviral drugs, reduce the occurrence of transmitted resistance, and prevent and control them. HIV-1 resistance testing methods are numerous and various depending on the application scenarios. This paper summarizes many literatures around the world and comprehensively discusses HIV-1 drug resistance testing methods.
ISSN:1005-930X