Antidepressant-like activity of Bezafibrate in mice models of depression: a behavioral and neurobiological characterization

Antidepressant-like activity of Bezafibrate in mice models of depression: a behavioral and neurobiological characterization

BackgroundDepression represents a major global public health challenge, inflicting profound suffering on patients while imposing substantial socioeconomic burdens on families and healthcare systems. Although monoamine-based antidepressants remain first-line pharmacotherapy, accumulating clinical evi...

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Main Authors:	Dawei Xu, Jin Zhou, Siyi Zhou, Weizhen Wang, Chengniu Wang, Bo Jiang, Wei Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Series:	Frontiers in Pharmacology
Subjects:	Bezafibrate depression PPARα BNDF CUMS
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1595341/full
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