Basic Fibroblast Growth Factor-Mediated Overexpression of Vascular Endothelial Growth Factor in 1F6 Human Melanoma Cells is Regulated by Activation of PI-3K and p38 MAPK
Background: 1F6 human melanoma xenografts overexpressing either the 18 kD (18kD) form or all (ALL) forms of human basic fibroblast growth factor (bFGF) demonstrate an abundant number of microvessels and accelerated growth. We now examined whether bFGF mediates vascular endothelial growth factor (VEG...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.3233/CLO-2009-0477 |
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| _version_ | 1850233839855599616 |
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| author | Dennis Fontijn Linda J. W. Bosch Monique C. A. Duyndam Maria P. A. van Berkel Maarten L. Janmaat Epie Boven |
| author_facet | Dennis Fontijn Linda J. W. Bosch Monique C. A. Duyndam Maria P. A. van Berkel Maarten L. Janmaat Epie Boven |
| author_sort | Dennis Fontijn |
| collection | DOAJ |
| description | Background: 1F6 human melanoma xenografts overexpressing either the 18 kD (18kD) form or all (ALL) forms of human basic fibroblast growth factor (bFGF) demonstrate an abundant number of microvessels and accelerated growth. We now examined whether bFGF mediates vascular endothelial growth factor (VEGF) expression. |
| format | Article |
| id | doaj-art-07961eb7ef4e430298c638fe4bd4664a |
| institution | OA Journals |
| issn | 1570-5870 1875-8606 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cellular Oncology |
| spelling | doaj-art-07961eb7ef4e430298c638fe4bd4664a2025-08-20T02:02:50ZengWileyCellular Oncology1570-58701875-86062009-01-0131317919010.3233/CLO-2009-0477Basic Fibroblast Growth Factor-Mediated Overexpression of Vascular Endothelial Growth Factor in 1F6 Human Melanoma Cells is Regulated by Activation of PI-3K and p38 MAPKDennis Fontijn0Linda J. W. Bosch1Monique C. A. Duyndam2Maria P. A. van Berkel3Maarten L. Janmaat4Epie Boven5Department of Medical Oncology, VU University Medical Center, Amsterdam, The NetherlandsDepartment of Medical Oncology, VU University Medical Center, Amsterdam, The NetherlandsDepartment of Medical Oncology, VU University Medical Center, Amsterdam, The NetherlandsDepartment of Medical Oncology, VU University Medical Center, Amsterdam, The NetherlandsDepartment of Medical Oncology, VU University Medical Center, Amsterdam, The NetherlandsDepartment of Medical Oncology, VU University Medical Center, Amsterdam, The NetherlandsBackground: 1F6 human melanoma xenografts overexpressing either the 18 kD (18kD) form or all (ALL) forms of human basic fibroblast growth factor (bFGF) demonstrate an abundant number of microvessels and accelerated growth. We now examined whether bFGF mediates vascular endothelial growth factor (VEGF) expression.http://dx.doi.org/10.3233/CLO-2009-0477 |
| spellingShingle | Dennis Fontijn Linda J. W. Bosch Monique C. A. Duyndam Maria P. A. van Berkel Maarten L. Janmaat Epie Boven Basic Fibroblast Growth Factor-Mediated Overexpression of Vascular Endothelial Growth Factor in 1F6 Human Melanoma Cells is Regulated by Activation of PI-3K and p38 MAPK Cellular Oncology |
| title | Basic Fibroblast Growth Factor-Mediated Overexpression of Vascular Endothelial Growth Factor in 1F6 Human Melanoma Cells is Regulated by Activation of PI-3K and p38 MAPK |
| title_full | Basic Fibroblast Growth Factor-Mediated Overexpression of Vascular Endothelial Growth Factor in 1F6 Human Melanoma Cells is Regulated by Activation of PI-3K and p38 MAPK |
| title_fullStr | Basic Fibroblast Growth Factor-Mediated Overexpression of Vascular Endothelial Growth Factor in 1F6 Human Melanoma Cells is Regulated by Activation of PI-3K and p38 MAPK |
| title_full_unstemmed | Basic Fibroblast Growth Factor-Mediated Overexpression of Vascular Endothelial Growth Factor in 1F6 Human Melanoma Cells is Regulated by Activation of PI-3K and p38 MAPK |
| title_short | Basic Fibroblast Growth Factor-Mediated Overexpression of Vascular Endothelial Growth Factor in 1F6 Human Melanoma Cells is Regulated by Activation of PI-3K and p38 MAPK |
| title_sort | basic fibroblast growth factor mediated overexpression of vascular endothelial growth factor in 1f6 human melanoma cells is regulated by activation of pi 3k and p38 mapk |
| url | http://dx.doi.org/10.3233/CLO-2009-0477 |
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